The efficacy of amantadine in the symptomatic treatment of patients with Parkinson's
disease, discovered serendipitously more than 50 years ago, has stood the test of time and …

Over the decades, pharmaceutical treatments, particularly dopaminergic (DAergic) drugs
have been considered as the main therapy against motor symptoms of Parkinson's disease …

Background: In Parkinson's disease (PD), impulse control disorders (ICDs) develop as side-
effect of dopaminergic replacement therapy (DRT). Cognitive, affective, and motivational …

Impulse control disorders (ICDs) in Parkinson's disease (PD) are aberrant behavior such as
pathological gambling, hypersexuality, binge eating, and compulsive buying, which typically …

Abstract Impulse Control Disorders (ICD) are associated with impairment in cognitive
flexibility and cortical inhibition. In Parkinson's Disease (PD) the relationship between ICD …

Background Gambling disorder (GD) is defined as persistent and recurrent problematic
gambling behavior leading to clinically significant impairment or distress. The prevalence of …

It has been well documented that deep brain stimulation (DBS) of the subthalamic nucleus
(STN) to address some of the disabling motor symptoms of Parkinson's disease (PD) can …

Introduction: Amantadine is an old, antiviral compound that moderately ameliorates impaired
motor behaviour in Parkinson's disease. Its current resurgence results from the novel …

Introduction Impulse control behaviors (ICB s) are impulsive–compulsive behaviors often
associated with dopamine replacement therapy in Parkinson's disease (PD). Although …

Background and Objectives: Parkinson's disease (PD) is one of the most common
neurodegenerative diseases in the world. It is characterized by the presence of not only …