A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface
of a wide variety of samples, allowing the multiplex measurement of both abundance and …

Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a
powerful tool for investigating the distribution of proteins and small molecules within …

Imaging MS (IMS) is an emerging technology that permits the direct analysis and
determination of the distribution of molecules in tissue sections. Biological molecules such …

MALDI imaging mass spectrometry (MALDI-IMS) has become a powerful tool for the
detection and localization of drugs, proteins, and lipids on-tissue. Nevertheless, this …

Purpose: Histopathology is the standard approach for tissue diagnostics and centerpiece of
pathology. Although the current system provides prognostic information, there is need for …

Imaging using MS has the potential to deliver highly parallel, multiplexed data on the
specific localization of molecular ions in tissue samples directly, and to measure and map …

A decade after its inception, MALDI imaging mass spectrometry has become a unique
technique in the proteomics arsenal for biomarker hunting in a variety of diseases. At this …

Significant progress in instrumentation and sample preparation approaches have recently
expanded the potential of MALDI imaging mass spectrometry to the analysis of …

Gangliosides are particularly abundant in the central nervous system (CNS) and thought to
play important roles in memory formation, neuritogenesis, synaptic transmission, and other …