Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Bacterial exo-polysaccharides in biofilms: role in antimicrobial resistance and treatments

S Singh, S Datta, KB Narayanan… - Journal of Genetic …, 2021 - Springer
Background Bacterial biofilms are aggregation or collection of different bacterial cells which
are covered by self-produced extracellular matrix and are attached to a substratum …

Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

Current challenges and future opportunities of phage therapy

DP Pires, AR Costa, G Pinto, L Meneses… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Phages for biofilm removal

C Ferriol-González, P Domingo-Calap - Antibiotics, 2020 - mdpi.com
Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …

Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication

E Maffei, AK Woischnig, MR Burkolter, Y Heyer… - Nature …, 2024 - nature.com
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

Staphylococcal biofilms: Challenges and novel therapeutic perspectives

C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Evolutionary causes and consequences of bacterial antibiotic persistence

E Bakkeren, M Diard, WD Hardt - Nature Reviews Microbiology, 2020 - nature.com
Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

Bacterial biofilm destruction: A focused review on the recent use of phage-based strategies with other antibiofilm agents

S Amankwah, K Abdella, T Kassa - Nanotechnology, science and …, 2021 - Taylor & Francis
Biofilms are bacterial communities that live in association with biotic or abiotic surfaces and
enclosed in an extracellular polymeric substance. Their formation on both biotic and abiotic …

Treating bacterial infections with bacteriophage-based enzybiotics: in vitro, in vivo and clinical application

KM Danis-Wlodarczyk, DJ Wozniak, ST Abedon - Antibiotics, 2021 - mdpi.com
Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …