Controversies in the pathogenesis, diagnosis and treatment of PCOS: focus on insulin resistance, inflammation, and hyperandrogenism

D Armanini, M Boscaro, L Bordin… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …

Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Current guidelines for diagnosing PCOS

JP Christ, MI Cedars - Diagnostics, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive-
aged women. Much of the confusion surrounding PCOS diagnosis stems from the broad …

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome

HJ Teede, ML Misso, MF Costello, A Dokras… - Human …, 2018 - academic.oup.com
STUDY QUESTION What is the recommended assessment and management of women with
polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise …

Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

S Abraham Gnanadass, Y Divakar Prabhu… - Archives of Gynecology …, 2021 - Springer
Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

A novel and compact review on the role of oxidative stress in female reproduction

J Lu, Z Wang, J Cao, Y Chen, Y Dong - Reproductive Biology and …, 2018 - Springer
In recent years, the study of oxidative stress (OS) has become increasingly popular. In
particular, the role of OS on female fertility is very important and has been focused on …

Polycystic ovary syndrome

R Azziz, E Carmina, ZJ Chen, A Dunaif… - Nature reviews Disease …, 2016 - nature.com
Polycystic ovary syndrome (PCOS) affects 5–20% of women of reproductive age worldwide.
The condition is characterized by hyperandrogenism, ovulatory dysfunction and polycystic …

The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis

G Bozdag, S Mumusoglu, D Zengin… - Human …, 2016 - academic.oup.com
STUDY QUESTION What is the reported overall prevalence of polycystic ovary syndrome
(PCOS) according to the criteria of the National Institutes of Health (NIH), Rotterdam or the …

Ovulation: parallels with inflammatory processes

DM Duffy, CM Ko, M Jo, M Brannstrom… - Endocrine …, 2019 - academic.oup.com
The midcycle surge of LH sets in motion interconnected networks of signaling cascades to
bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators …