Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a
fundamental role in mediating the onset and progression of disease. Microglia, which …

Microglia are the only immune cells that permanently reside in the central nervous system
(CNS) alongside neurons and other types of glial cells. The past decade has witnessed a …

The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

Innate immunity within the central nervous system (CNS) is primarily provided by resident
microglia. Microglia are pivotal in immune surveillance and also facilitate the co‐ordinated …

Aging of the central nervous system (CNS) is one of the major risk factors for the
development of neurodegenerative pathologies such as Parkinson's disease (PD) and …

Glia of the central nervous system (CNS) help to maintain homeostasis in the brain and
support efficient neuronal function. Microglia are innate immune cells of the brain that …

Microglia are the primary immune cells of the central nervous system that help nourish and
support neurons, clear debris, and respond to foreign stimuli. Greatly impacted by their …

DNA damage contributes to brain aging and neurodegenerative diseases. However, the
factors stimulating DNA repair to stave off functional decline remain obscure. We show that …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Traumatic brain injury (TBI) can lead to secondary neuropsychiatric problems that develop
and persist years after injury. Mounting evidence indicates that neuroinflammatory …