The role of cytokines in the pathogenesis of schizophrenia

B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …

Could CRP be a differential biomarker of illness stages in schizophrenia? A systematic review and meta-analysis

V Lestra, B Romeo, C Martelli, A Benyamina… - Schizophrenia …, 2022 - Elsevier
Background Patients with schizophrenia display peripheral inflammation but the impact of
illness phase is not clear. Our meta-analysis investigated the difference in CRP levels …

Serum interleukin-6 in schizophrenia: a system review and meta-analysis

X Zhou, B Tian, HB Han - Cytokine, 2021 - Elsevier
Background Schizophrenia is a disabling serious mental illness with unknown etiology.
Inflammatory abnormalities play an important role in the pathogenesis of the disease. Many …

Is it time for a paradigm shift in the treatment of schizophrenia? the use of inflammation-reducing and neuroprotective Drugs—A review

A Messina, C Concerto, A Rodolico, A Petralia… - Brain Sciences, 2023 - mdpi.com
Comprehending the pathogenesis of schizophrenia represents a challenge for global
mental health. To date, although it is evident that alterations in dopaminergic, serotonergic …

Regulation of reactive oxygen species-mediated damage in the pathogenesis of schizophrenia

S Madireddy, S Madireddy - Brain Sciences, 2020 - mdpi.com
The biochemical integrity of the brain is paramount to the function of the central nervous
system, and oxidative stress is a key contributor to cerebral biochemical impairment …

Immunologic profiling in schizophrenia and rheumatoid arthritis

WW Eaton, KM Rodriguez, MA Thomas, J Johnson… - Psychiatry …, 2022 - Elsevier
The negative relationship between schizophrenia (SCZ) and rheumatoid arthritis (RA) has
been observed for 85 years, but the mechanisms driving this association are unknown. This …

[HTML][HTML] Anti-inflammatory diets and schizophrenia

HY Cha, SJ Yang - Clinical nutrition research, 2020 - ncbi.nlm.nih.gov
Schizophrenia is a mental illness characterized by symptoms such as hallucinations,
delusions, disorganized speech, disorganized or catatonic behavior, and negative …

Acute ketamine induces neuronal hyperexcitability and deficits in prepulse inhibition by upregulating IL-6

Y Luo, Y Yu, H He, N Fan - Progress in Neuro-Psychopharmacology and …, 2024 - Elsevier
Acute ketamine administration results in psychotic symptoms similar to those observed in
schizophrenia and is regarded as a pharmacological model of schizophrenia. Accumulating …

RETRACTED: Pentoxifylline as an adjunctive in treatment of negative symptoms in chronic schizophrenia: A double‐blind, randomized, placebo‐controlled trial

MS Abdallah, EM Mosalam, A Hassan… - CNS Neuroscience …, 2023 - Wiley Online Library
Aim The aim of this study was to explore the effectiveness and safety of pentoxifylline as an
adjuvant to risperidone in mitigating the negative symptoms in patients with chronic …

[HTML][HTML] Маркеры воспаления при шизофрении для науки и практики

СА Зозуля, ЗВ Сарманова, ИН Отман, ТП Клюшник - Доктор. Ру, 2023 - cyberleninka.ru
Цель обзора: представить данные литературы и результаты собственных
исследований относительно воспалительных биомаркеров, выявляемых с …