Population genetics of African Schistosoma species

O Rey, BL Webster, T Huyse, D Rollinson… - Infection, Genetics and …, 2021 - Elsevier
Blood flukes within the genus Schistosoma (schistosomes) are responsible for the major
disease, schistosomiasis, in tropical and sub-tropical areas. This disease is predominantly …

Drug resistance in vectorborne parasites: multiple actors and scenarios for an evolutionary arms race

M Vanaerschot, S Huijben… - FEMS microbiology …, 2014 - academic.oup.com
Drug-resistant pathogens emerge faster than new drugs come out of drug discovery
pipelines. Current and future drug options should therefore be better protected, requiring a …

Population Genetic Structure and Hybridization of Schistosoma haematobium in Nigeria

AM Onyekwere, O Rey, JF Allienne, MC Nwanchor… - Pathogens, 2022 - mdpi.com
Background: Schistosomiasis is a major poverty-related disease caused by dioecious
parasitic flatworms of the genus Schistosoma with a health impact on both humans and …

Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: implications for epidemiology …

CM Gower, AN Gouvras, PHL Lamberton, A Deol… - Acta tropica, 2013 - Elsevier
We conducted the first meta-analysis of ten Schistosoma haematobium (one published and
nine unpublished) and eight Schistosoma mansoni (two published and six unpublished) …

[HTML][HTML] Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre-and post-praziquantel treatment in Tanzania

AJ Norton, CM Gower, PHL Lamberton… - The American journal …, 2010 - ncbi.nlm.nih.gov
Recent shifts in global health policy have led to the implementation of mass drug
administration (MDA) for neglected tropical diseases. Here we show how population genetic …

No apparent reduction in schistosome burden or genetic diversity following four years of school-based mass drug administration in Mwea, central Kenya, a heavy …

AE Lelo, DN Mburu, GN Magoma… - PLoS Neglected …, 2014 - journals.plos.org
Background Schistosomiasis is a debilitating neglected tropical disease that infects over 200
million people worldwide. To combat this disease, in 2012, the World Health Organization …

Genetic evidence for the role of non-human primates as reservoir hosts for human schistosomiasis

T Kebede, N Bech, JF Allienne, R Olivier… - PLoS Neglected …, 2020 - journals.plos.org
Background Schistosomiasis is a chronic parasitic disease, that affects over 207 million
people and causes over 200,000 deaths annually, mainly in sub-Saharan Africa. Although …

Praziquantel Treatment Decreases Schistosoma mansoni Genetic Diversity in Experimental Infections

R Coeli, EH Baba, N Araujo, PMZ Coelho… - PLoS Neglected …, 2013 - journals.plos.org
Background Schistosomiasis has a considerable impact on public health in many tropical
and subtropical areas. In the new world, schistosomiasis is caused by the digenetic …

Applying evolutionary genetics to schistosome epidemiology

ML Steinauer, MS Blouin, CD Criscione - Infection, Genetics and Evolution, 2010 - Elsevier
We review how molecular markers and evolutionary analysis have been applied to the study
of schistosome parasites, important pathogens that infect over 200 million people worldwide …

Field-derived Schistosoma mansoni and Biomphalaria pfeifferi in Kenya: a compatible association characterized by lack of strong local adaptation, and presence of …

MW Mutuku, CK Dweni, M Mwangi, JM Kinuthia… - Parasites & vectors, 2014 - Springer
Background Schistosoma mansoni is widely distributed in sub-Saharan Africa with
Biomphalaria pfeifferi being its most widespread and important snail intermediate host. Few …