Conspectus Transition metal hydride catalyzed functionalization of remote and proximal
olefins has many advantages over conventional cross-coupling reactions. It avoids the …

Compounds rich in sp3-hybridized carbons are desirable in drug discovery. Nickel-
catalyzed hydrocarbonation of alkenes is a potentially efficient method to synthesize these …

Recent research in medicinal chemistry has suggested that there is a correlation between
an increase in the fraction of sp 3 carbons—those bonded to four other atoms—in drug …

Transformation of sterically hindered tertiary alkyl electrophiles under nickel-catalyzed
conditions to forge C (sp3)–C bonds and simultaneously create challenging all-carbon …

Design of ligands in transition-metal catalyzed reactions is challenging, especially in
asymmetric transformations. With each step in the catalytic cycle promoted by its privileged …

Regiodivergent alkene functionalization that produces either regioisomer starting from the
same raw materials is desirable. Herein, we report a nickel‐catalyzed switchable site …

Novel-substituted pyrrolidine derivatives are widely used in drugs and bioactive molecules.
The efficient synthesis of these valuable skeletons, especially enantiopure derivatives, is still …

Herein, an electrochemically driven NiH‐catalyzed reductive coupling of alkyl halides and
alkyl alkenes for the construction of Csp3− Csp3 bonds is firstly reported. Notably, alkyl …

Ni-catalyzed cross-electrophile coupling reactions have emerged as appealing methods to
construct organic molecules without the use of stoichiometric organometallic reagents. The …

Chiral alkyl amines are omnipresent as bioactive molecules and synthetic intermediates.
The catalytic and enantioselective synthesis of alkyl amines from readily accessible …