COVID-19, renin-angiotensin system and endothelial dysfunction

R Amraei, N Rahimi - Cells, 2020 - mdpi.com
The newly emergent novel coronavirus disease 2019 (COVID-19) outbreak, which is caused
by SARS-CoV-2 virus, has posed a serious threat to global public health and caused …

Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do …

L Minodier, RN Charrel, PE Ceccaldi, S van Der Werf… - Virology journal, 2015 - Springer
This review provides for the first time an assessment of the current understanding about the
occurrence and the clinical significance of gastrointestinal (GI) symptoms in influenza …

The amazing innate immune response to influenza A virus infection

S Tripathi, MR White, KL Hartshorn - Innate immunity, 2015 - journals.sagepub.com
Influenza A viruses (IAVs) remain a major health threat and a prime example of the
significance of innate immunity. Our understanding of innate immunity to IAV has grown …

[HTML][HTML] Advances in deciphering the interactions between viral proteins of influenza A virus and host cellular proteins

L Jiang, H Chen, C Li - Cell Insight, 2023 - Elsevier
Influenza A virus (IAV) poses a severe threat to the health of animals and humans. The
genome of IAV consists of eight single-stranded negative-sense RNA segments, encoding …

Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein …

S Tripathi, J Batra, W Cao, K Sharma, JR Patel… - Cell death & …, 2013 - nature.com
Apoptosis induction is an antiviral host response, however, influenza A virus (IAV) infection
promotes host cell death. The nucleoprotein (NP) of IAV is known to contribute to viral …

Molecular events involved in influenza A virus-induced cell death

R Gui, Q Chen - Frontiers in Microbiology, 2022 - frontiersin.org
Viral infection usually leads to cell death. Moderate cell death is a protective innate immune
response. By contrast, excessive, uncontrolled cell death causes tissue destruction, cytokine …

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial …

E Klaile, TE Klassert, I Scheffrahn, MM Müller… - Respiratory …, 2013 - Springer
Background The carcinoembryonic antigen (CEA)-related cell adhesion molecules
CEACAM1 (BGP, CD66a), CEACAM5 (CEA, CD66e) and CEACAM6 (NCA, CD66c) are …

Antiviral activity of probenecid and oseltamivir on Influenza virus replication

J Murray, DE Martin, FD Sancilio, RA Tripp - Viruses, 2023 - mdpi.com
Influenza can cause respiratory infections, leading to significant morbidity and mortality in
humans. While current influenza vaccines offer varying levels of protection, there remains a …

Orchestrated efforts on host network hijacking: Processes governing virus replication

X Dai, O Hakizimana, X Zhang, AC Kaushik, J Zhang - Virulence, 2020 - Taylor & Francis
With the high pervasiveness of viral diseases, the battle against viruses has never ceased.
Here we discuss five cellular processes, namely “autophagy”,“programmed cell …

Anti-influenza virus activity of benzo [d] thiazoles that target heat shock protein 90

A Lamut, M Gjorgjieva, L Naesens, S Liekens… - Bioorganic …, 2020 - Elsevier
Seasonal or pandemic influenza virus infections are a worldwide health problem requiring
antiviral therapy. Since virus resistance to the established neuraminidase inhibitors and …