The complement system in metabolic-associated kidney diseases

Z Xu, L Tao, H Su - Frontiers in Immunology, 2022 - frontiersin.org
Metabolic syndrome (MS) is a group of clinical abnormalities characterized by central or
abdominal obesity, hypertension, hyperuricemia, and metabolic disorders of glucose or lipid …

Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)‐driven Complement‐mediated Diseases

BG Gibson, TE Cox, KJ Marchbank - Immunological Reviews, 2023 - Wiley Online Library
This review aimed to capture the key findings that animal models have provided around the
role of the alternative pathway and amplification loop (AP/AL) in disease. Animal models …

New insights of acylation stimulating protein in modulating the pathological progression of metabolic syndromes

X Lian, Y Cheng, H Kang - International Immunopharmacology, 2024 - Elsevier
Obesity is associated with insulin resistance, hypertension, and coronary artery diseases
which are grouped as metabolic syndrome. Rather than being a storage for energy, the …