Origins of DNA replication in eukaryotes

Y Hu, B Stillman - Molecular cell, 2023 - cell.com
Errors occurring during DNA replication can result in inaccurate replication, incomplete
replication, or re-replication, resulting in genome instability that can lead to diseases such as …

Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease

IA Qureshi, MF Mehler - Nature Reviews Neuroscience, 2012 - nature.com
Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a
rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture …

Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and …

BWM Van Balkom, AS Eisele, DM Pegtel… - Journal of …, 2015 - Taylor & Francis
Exosomes are small vesicles that mediate cell–cell communication. They contain proteins,
lipids and RNA, and evidence is accumulating that these molecules are specifically sorted …

Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL‐10 expression and secretion

L Cambier, G de Couto, A Ibrahim… - EMBO Molecular …, 2017 - embopress.org
Cardiosphere‐derived cells (CDC s) reduce myocardial infarct size via secreted
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …

[HTML][HTML] Functional roles of non-coding Y RNAs

MP Kowalski, T Krude - The international journal of biochemistry & cell …, 2015 - Elsevier
Non-coding RNAs are involved in a multitude of cellular processes but the biochemical
function of many small non-coding RNAs remains unclear. The family of small non-coding Y …

Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects

A Yeri, A Courtright, R Reiman, E Carlson, T Beecroft… - Scientific reports, 2017 - nature.com
Interest in circulating RNAs for monitoring and diagnosing human health has grown
significantly. There are few datasets describing baseline expression levels for total cell-free …

The Pol III transcriptome: basic features, recurrent patterns, and emerging roles in cancer

S Zhou, K Van Bortle - Wiley Interdisciplinary Reviews: RNA, 2023 - Wiley Online Library
Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short,
highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III …

The circulating transcriptome as a source of cancer liquid biopsy biomarkers

C Sole, E Arnaiz, L Manterola, D Otaegui… - Seminars in cancer …, 2019 - Elsevier
Non-invasive biomarkers or liquid biopsies have the potential to revolutionise cancer patient
management as repeated sampling allows real-time monitoring of disease progression and …

Peaks cloaked in the mist: the landscape of mammalian replication origins

O Hyrien - Journal of Cell Biology, 2015 - rupress.org
Replication of mammalian genomes starts at sites termed replication origins, which
historically have been difficult to locate as a result of large genome sizes, limited power of …

Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line

M Chen, R Xu, H Ji, DW Greening, A Rai… - Scientific reports, 2016 - nature.com
Previously we reported that LIM1863 colorectal cancer (CRC) cells secrete three distinct
extracellular vesicle subtypes–two subpopulations of exosomes (apical EpCAM-Exos and …