The entorhinal cortex (EC) is the brain region that often exhibits the earliest histological
alterations in Alzheimer's disease (AD), including the formation of neurofibrillary tangles and …

Context is widely regarded as a major determinant of learning and memory across
numerous domains, including classical and instrumental conditioning, episodic memory …

The hippocampal-entorhinal system is important for spatial and relational memory tasks. We
formally link these domains, provide a mechanistic understanding of the hippocampal role in …

BACKGROUND Ever since Edward Tolman's proposal that comprehensive cognitive maps
underlie spatial navigation and, more generally, psychological functions, the question of …

Memories of past events can be recalled long after the event, indicating stability. But new
experiences are also integrated into existing memories, indicating plasticity. In the …

Viewpoints: how the hippocampus contributes to memory, navigation and cognition | Nature
Neuroscience Skip to main content Thank you for visiting nature.com. You are using a browser …

Arguably, the most difficult part of learning is deciding what to learn about. Should I
associate the positive outcome of safely completing a street-crossing with the situation 'the …

The hippocampal system is critical for storage and retrieval of declarative memories,
including memories for locations and events that take place at those locations. Spatial …

The ability to discriminate among similar experiences is a crucial feature of episodic
memory. This ability has long been hypothesized to require the hippocampus, and …

The hippocampus is critical to remembering the flow of events in distinct experiences and, in
doing so, bridges temporal gaps between discontiguous events. Here, we report a robust …