High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

DL Schmitt, P Dranchak, P Parajuli, D Blivis, T Voss… - Plos one, 2023 - journals.plos.org
We have previously demonstrated that human liver-type phosphofructokinase 1 (PFK1)
recruits other rate-determining enzymes in glucose metabolism to organize multienzyme …

Size-specific modulation of a multienzyme glucosome assembly during the cell cycle

M Jeon, DL Schmitt, M Kyoung, S An - ACS bio & med Chem Au, 2023 - ACS Publications
Enzymes in glucose metabolism have been subjected to numerous studies, revealing the
importance of their biological roles during the cell cycle. However, due to the lack of viable …

Mechanistic insights into condensate formation of human liver-type phosphofructokinase by stochastic modeling approaches

HW Kang, L Nguyen, S An, M Kyoung - Scientific Reports, 2024 - nature.com
Human liver-type phosphofructokinase 1 (PFKL) has been shown to regulate glucose flux as
a scaffolder arranging glycolytic and gluconeogenic enzymes into a multienzyme metabolic …

High-content quantitative high-throughput screening identifies a cell cycle-associated signaling cascade that regulates a multienzyme metabolic assembly for glucose …

DL Schmitt, P Dranchak, P Parajuli, D Blivis, T Voss… - bioRxiv, 2022 - biorxiv.org
We have previously demonstrated that human liver-type phosphofructokinase 1 (PFK1)
recruits other rate-determining enzymes in glucose metabolism to organize multienzyme …

Mechanistic insights of glucosome condensate formation by stochastic modeling approaches

HW Kang, L Nguyen, S An, M Kyoung - bioRxiv, 2022 - biorxiv.org
Human liver-type phosphofructokinase 1 (PFKL) has been shown to play a scaffolder role to
recruit and organize glycolytic and gluconeogenic enzymes into a multienzyme metabolic …