Elevated plasma concentrations of lipoprotein (a)[Lp (a)] have been determined to be a
causal risk factor for coronary heart disease, and may similarly play a role in other …

Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …

Elevated plasma concentrations of lipoprotein (a)(Lp (a)) are a causal risk factor for the
development of atherothrombotic disorders including coronary heart disease. However, the …

Increased lipoprotein (a)(Lp (a)) levels are an independent predictor of coronary artery
disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD …

In the vasculature, reactive oxidant species, including reactive oxygen, nitrogen, or
halogenating species, and thiyl, tyrosyl, or protein radicals may oxidatively modify lipids and …

Antibodies to oxidized LDL (oxLDL) may be associated with improved outcomes in
cardiovascular disease. However, analysis is restricted by heterogenous study design and …

Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are characterized by
excessive intraalveolar fibrin deposition, driven, at least in part by inflammation. The …

Enhanced coagulation and thrombosis are linked to a variety of cardiovascular and
metabolic diseases, as well as to cancer. Many of these diseases are also associated with …

One of the most prominent actions of oxidative stress is the attack of free radicals on
poylyunsaturated fatty acids (PUFAs), initiating a chain reaction to modify these PUFAs and …

Antithrombin (AT), in the presence of heparin, is able to inhibit the catalytic activity of factor
VIIa bound to tissue factor (TF) on cell surfaces. The clinical meaning of FVIIa-AT complexes …