New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily

J Song, Y He, C Luo, B Feng, F Ran, H Xu, Z Ci… - Pharmacological …, 2020 - Elsevier
Protocatechuic acid is a natural phenolic acid, which widely exists in our daily diet and
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …

Gallic acid and diabetes mellitus: its association with oxidative stress

Y Xu, G Tang, C Zhang, N Wang, Y Feng - Molecules, 2021 - mdpi.com
Diabetes mellitus (DM) is a severe chronic metabolic disease with increased mortality and
morbidity. The pathological progression of DM is intimately connected with the formation and …

[HTML][HTML] Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

[HTML][HTML] Gallic acid: A promising bioactive agent for food preservation and sustainable packaging development

I Rahmawati, AW Pratama, SA Pratama… - Case Studies in …, 2024 - Elsevier
The growing global population challenges the food industry to ensure it remains safe for
consumption. Food waste caused by imbalances between production and handling creates …

A comprehensive review of the classification, sources, biosynthesis, and biological properties of hydroxybenzoic and hydroxycinnamic acids

APG da Silva, WG Sganzerla, OD John… - Phytochemistry …, 2023 - Springer
Simple phenolic acids are considered the most common and widely studied bioactive
compounds belonging to plants' secondary metabolites. The simple phenolic acids can be …

Methodologies in the Analysis of Phenolic Compounds in Roselle (Hibiscus sabdariffa L.): Composition, Biological Activity, and Beneficial Effects on Human Health

BW Hapsari, W Setyaningsih - Horticulturae, 2021 - mdpi.com
Roselle (Hibiscus sabdariffa L.), as an edible flower, has long provided an array of positive
effects on human health. This benefit is a result of phenolic compounds that are naturally …

Hibiscus sabdariffa in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review

D Jamrozik, W Borymska, I Kaczmarczyk-Żebrowska - Foods, 2022 - mdpi.com
Diabetes is currently a global health problem that is already reported as an epidemic. This
metabolic disease, characterized by a disturbance in the carbohydrate, protein, and lipid …

Research progress on intervention effect and mechanism of protocatechuic acid on nonalcoholic fatty liver disease

Y Gao, R Tian, H Liu, H Xue, R Zhang… - Critical Reviews in …, 2022 - Taylor & Francis
Nonalcoholic fatty liver disease (NAFLD) has become a surge burden worldwide due to its
high prevalence, with complicated deterioration symptoms such as liver fibrosis and cancer …

[HTML][HTML] Food supplements could be an effective improvement of diabetes mellitus: a review

X Meng, Q Li, R Shi, J Chang, H Chang, M Li - Journal of Future Foods, 2021 - Elsevier
Diabetes mellitus is a disease of endocrine and metabolism disorders, characterized by
hyperglycemia, and increased risk of cardiovascular disease complications. Although oral …

The antidiabetic and antilipidemic effects of Hibiscus sabdariffa: A systematic review and meta-analysis of randomized clinical trials

M Bule, AH Albelbeisi, S Nikfar, M Amini… - Food Research …, 2020 - Elsevier
Hibiscus sabdariffa (HS) is a woody-based subshrub of the Malvaceae family which has
various uses in traditional medicine. This review systematically evaluates the evidence from …