Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma
The lack of representative nasopharyngeal carcinoma (NPC) models has seriously
hampered research on EBV carcinogenesis and preclinical studies in NPC. Here we report …
hampered research on EBV carcinogenesis and preclinical studies in NPC. Here we report …
Candidate probiotic Lactiplantibacillus plantarum HNU082 rapidly and convergently evolves within human, mice, and zebrafish gut but differentially influences the …
Background Improving probiotic engraftment in the human gut requires a thorough
understanding of the in vivo adaptive strategies of probiotics in diverse contexts. However …
understanding of the in vivo adaptive strategies of probiotics in diverse contexts. However …
Toward reliable biomarker signatures in the age of liquid biopsies-how to standardize the small RNA-Seq workflow
D Buschmann, A Haberberger, B Kirchner… - Nucleic Acids …, 2016 - academic.oup.com
Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression
profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA …
profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA …
Oncological and genetic factors impacting PDX model construction with NSG mice in pancreatic cancer
S Guo, S Gao, R Liu, J Shen, X Shi, S Bai… - The FASEB …, 2019 - Wiley Online Library
ABSTRACT A patient‐derived xenograft (PDX) approach, which relies on direct
transplantation of tumor specimens into an immunocompromised animal, is a commonly …
transplantation of tumor specimens into an immunocompromised animal, is a commonly …
Differential contributions of sarcomere and mitochondria-related multigene variants to the endophenotype of hypertrophic cardiomyopathy
H Chung, Y Kim, SM Cho, HJ Lee, CH Park, JY Kim… - Mitochondrion, 2020 - Elsevier
Background Hypertrophic cardiomyopathy (HCM) is a multigenic disease that occurs due to
various genetic modifiers. We investigated phenotype-based clinical and genetic …
various genetic modifiers. We investigated phenotype-based clinical and genetic …
Use of fetal magnetic resonance image analysis and machine learning to predict the need for postnatal cerebrospinal fluid diversion in fetal ventriculomegaly
Importance Which children with fetal ventriculomegaly, or enlargement of the cerebral
ventricles in utero, will develop hydrocephalus requiring treatment after birth is unclear …
ventricles in utero, will develop hydrocephalus requiring treatment after birth is unclear …
[PDF][PDF] SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from …
SH Kim, WS Park, J Chung - Investigative and Clinical …, 2019 - synapse.koreamed.org
Purpose Multilocular cystic renal neoplasm of low malignant potential (MCRNLMP) and
clear cell renal cell carcinoma with cystic change (MCRCC) have different prognoses …
clear cell renal cell carcinoma with cystic change (MCRCC) have different prognoses …
Recalibration of mapping quality scores in Illumina short-read alignments improves SNP detection results in low-coverage sequencing data
E Cline, N Wisittipanit, T Boongoen, E Chukeatirote… - PeerJ, 2020 - peerj.com
Background Low-coverage sequencing is a cost-effective way to obtain reads spanning an
entire genome. However, read depth at each locus is low, making sequencing error difficult …
entire genome. However, read depth at each locus is low, making sequencing error difficult …
Contribution of sarcomere gene mutations to left atrial function in patients with hypertrophic cardiomyopathy
H Chung, Y Kim, CH Park, IS Kim, JY Kim… - Cardiovascular …, 2021 - Springer
Background Left atrial (LA) enlargement and dysfunction are related to clinical course in
patients with hypertrophic cardiomyopathy (HCM). We aimed to investigate genetic …
patients with hypertrophic cardiomyopathy (HCM). We aimed to investigate genetic …
Recessive variants in MYO1C as a potential novel cause of proteinuric kidney disease
Background Steroid-resistant nephrotic syndrome is the second leading cause of chronic
kidney disease among patients< 25 years of age. Through exome sequencing, identification …
kidney disease among patients< 25 years of age. Through exome sequencing, identification …