The case for precision medicine in the prevention, diagnosis, and treatment of cardiometabolic diseases in low-income and middle-income countries

S Misra, CA Aguilar-Salinas, T Chikowore… - The Lancet Diabetes & …, 2023 - thelancet.com
Cardiometabolic diseases are the leading preventable causes of death in most
geographies. The causes, clinical presentations, and pathogenesis of cardiometabolic …

The Multifaceted S100B Protein: A Role in Obesity and Diabetes?

F Michetti, G Di Sante, ME Clementi, F Valeriani… - International Journal of …, 2024 - mdpi.com
The S100B protein is abundant in the nervous system, mainly in astrocytes, and is also
present in other districts. Among these, the adipose tissue is a site of concentration for the …

Werner Syndrome and Diabetes: Opportunities for Precision Medicine

KB Kaylan, LH Philipson - Diabetes Care, 2024 - Am Diabetes Assoc
The precision diagnosis of diabetes is an increasingly important part of understanding the
full spectrum of disease heterogeneity, and several groups have recently outlined current …

The enduring metabolic improvement of combining dual amylin and calcitonin receptor agonist and semaglutide treatments in a rat model of obesity and diabetes

AT Larsen, KE Mohamed… - American Journal …, 2024 - journals.physiology.org
Long-acting dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates
for the treatment of type 2 diabetes and obesity due to their beneficial effects on body weight …

A Multi-Targeted Approach of Garcinol for Obesity Intervention: Mechanistic Insights and Possible Clinical Applications

MFA Bakar - PharmaNutrition, 2024 - Elsevier
Abstract Background Derived from Garcinia plants, garcinol has gained prominence for its
versatile health benefits, ranging from antioxidant and anti-inflammatory properties to …

Tracking correlations and predictors of plasma glucose in young adulthood: A comprehensive analysis from adolescence to young adulthood in TLGS study

A Ramezankhani, F Azizi, F Hadaegh - Diabetes Research and Clinical …, 2024 - Elsevier
Aims We investigated the tracking correlations between fasting plasma glucose (FPG) in
adolescence with both FPG and 2-hour post-load glucose (2 h-PG) in adulthood, and …

Exploring Flavonoid Intake and All-Cause Mortality in Diverse Health Conditions: Insights from NHANES 2007-2010 and 2017-2018

S Wang, F Xiong, Y Liu, Z Feng - Nutrition, 2024 - Elsevier
Objective: Flavonoids exhibit antioxidative, anti-inflammatory, and anticancer properties, yet
the relationship between flavonoid intake and all-cause mortality in the obese population …

糖尿病分型新视野--基于临床表现向基于病因分子机制转变.

杨舒婷, 罗说明, 周智广 - Journal of Practical Medicine …, 2024 - search.ebscohost.com
随着医学科技进步和对疾病本质理解的深入, 糖尿病的分型正经历着变革, 传统基于临床特征和
胰岛素依赖性的分类方法逐渐显示出其局限性. 近年来, 基因组, 表观遗传, 代谢组学等生物信息 …

Single‐Administration Self‐Boosting Microneedle Patch for the Treatment of Obesity

P Singh, T Vinikoor, N Sharma, N Nelson… - Advanced … - Wiley Online Library
Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are one of the most effective
treatments for obesity. The current therapy associated with repeated subcutaneous …

Investigating the Impact of Flavonoid Intake on All-Cause Mortality in Non-Obesity and Obesity with Various Complication: Insights from the National Health and …

S Wang, F Xiong, Y Liu, Z Feng - 2023 - researchsquare.com
Background: It is reported that dietary intake of flavonoid compounds can reduce all-cause
mortality and mortality from specific vascular diseases and cancers, but whether dietary …