Structural and functional alterations to the gut microbiome, referred to as gut dysbiosis, have
emerged as potential key mediators of neurodegeneration and Alzheimer disease (AD) …

The concept of insulin resistance has been around since a few decades after the discovery
of insulin itself. To allude to the classic Charles Dicken's novel published 62 years before the …

The concept of eco-evolutionary (eco-evo) dynamics, stating that ecological and
evolutionary processes occur at similar time scales and influence each other, has …

Gut microbiota (GM), the microorganisms in the gastrointestinal tract, contribute to the
regulation of brain homeostasis through bidirectional communication between the gut and …

With the aging of the world population and advances in medical and health technology,
more and more elderly patients are undergoing anesthesia and surgery, and perioperative …

There is now a convincing body of evidence from observational studies that the majority of
modifiable Alzheimer's disease and related dementia (ADRD) risk factors are vascular in …

Alzheimer's disease (AD) is associated with cognitive impairments and age-dependent
memory deficits which have been studied using genetic models of AD. Whether the …

Plasma apolipoprotein E levels were previously associated with the risk of developing
Alzheimer's disease (AD), levels of cerebrospinal fluid AD biomarkers, cognition and …

Increasing research links the gut microbiome to neurodegenerative disorders. The gut
microbiome communicates with the central nervous system via the gut–brain axis and affects …

Exposure to second-hand Smoke (SHS) remains prevalent. The underlying mechanisms of
how SHS affects the brain require elucidation. We tested the hypothesis that SHS inhalation …