Metabolites as signalling molecules

SA Baker, J Rutter - Nature reviews molecular cell Biology, 2023 - nature.com
Traditional views of cellular metabolism imply that it is passively adapted to meet the
demands of the cell. It is becoming increasingly clear, however, that metabolites do more …

Environmental influences on the pace of brain development

UA Tooley, DS Bassett, AP Mackey - Nature Reviews Neuroscience, 2021 - nature.com
Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

Development of prefrontal cortex

SM Kolk, P Rakic - Neuropsychopharmacology, 2022 - nature.com
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

Brain organoids for the study of human neurobiology at the interface of in vitro and in vivo

I Chiaradia, MA Lancaster - Nature Neuroscience, 2020 - nature.com
Brain development is an extraordinarily complex process achieved through the spatially and
temporally regulated release of key patterning factors. In vitro neurodevelopmental models …

A deep learning approach for Parkinson's disease diagnosis from EEG signals

SL Oh, Y Hagiwara, U Raghavendra, R Yuvaraj… - Neural Computing and …, 2020 - Springer
An automated detection system for Parkinson's disease (PD) employing the convolutional
neural network (CNN) is proposed in this study. PD is characterized by the gradual …

Maternal nutrition and neurodevelopment: a scoping review

MC Cortés-Albornoz, DP García-Guáqueta… - Nutrients, 2021 - mdpi.com
In this scoping review, we examined the association between maternal nutrition during
pregnancy and neurodevelopment in offspring. We searched the Pubmed and …

Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders

KE Zengeler, JR Lukens - Nature Reviews Immunology, 2021 - nature.com
The immune and nervous systems have unique developmental trajectories that individually
build intricate networks of cells with highly specialized functions. These two systems have …

Effect of alcohol use on the adolescent brain and behavior

B Lees, LR Meredith, AE Kirkland, BE Bryant… - Pharmacology …, 2020 - Elsevier
Adolescence is a particularly vulnerable neurodevelopmental period marked by high rates
of engagement with risky alcohol use. This review summarizes the cognitive and neural …

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

UC Eze, A Bhaduri, M Haeussler, TJ Nowakowski… - Nature …, 2021 - nature.com
The human cortex comprises diverse cell types that emerge from an initially uniform
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …

The microglial innate immune receptor TREM2 is required for synapse elimination and normal brain connectivity

F Filipello, R Morini, I Corradini, V Zerbi, A Canzi… - Immunity, 2018 - cell.com
The triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial innate immune
receptor associated with a lethal form of early, progressive dementia, Nasu-Hakola disease …