Advances in magnetic nanoparticles for biomedical applications

VF Cardoso, A Francesko, C Ribeiro… - Advanced …, 2018 - Wiley Online Library
Magnetic nanoparticles (NPs) are emerging as an important class of biomedical functional
nanomaterials in areas such as hyperthermia, drug release, tissue engineering, theranostic …

Magnetic nanoparticles for cancer theranostics: Advances and prospects

X Li, W Li, M Wang, Z Liao - Journal of Controlled Release, 2021 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Nanoparticles have been
broadly studied and emerged as a novel approach in diagnosis and treatment of tumors …

Rekindling RNAi therapy: materials design requirements for in vivo siRNA delivery

B Kim, JH Park, MJ Sailor - Advanced materials, 2019 - Wiley Online Library
With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …

[HTML][HTML] PLK1, a potential target for cancer therapy

Z Liu, Q Sun, X Wang - Translational oncology, 2017 - Elsevier
Abstract Polo-like kinase 1 (PLK1) plays an important role in the initiation, maintenance, and
completion of mitosis. Dysfunction of PLK1 may promote cancerous transformation and drive …

Recent advances and future prospects of iron oxide nanoparticles in biomedicine and diagnostics

NVS Vallabani, S Singh - 3 Biotech, 2018 - Springer
Superparamagnetic iron oxide nanoparticles (SPIONs) are considered as chemically inert
materials and, therefore, being extensively applied in the areas of imaging, targeting, drug …

Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy

L Zhu, Z Zhou, H Mao, L Yang - Nanomedicine, 2017 - Taylor & Francis
Recent advances in the development of magnetic nanoparticles (MNPs) have shown
promise in the development of new personalized therapeutic approaches for clinical …

[HTML][HTML] MRI-traceable theranostic nanoparticles for targeted cancer treatment

T Anani, S Rahmati, N Sultana, AE David - Theranostics, 2021 - ncbi.nlm.nih.gov
Current cancer therapies, including chemotherapy and radiotherapy, are imprecise, non-
specific, and are often administered at high dosages-resulting in side effects that severely …

Immune cell and stromal signature associated with progression-free survival of patients with resected pancreatic ductal adenocarcinoma

UM Mahajan, E Langhoff, E Goni, E Costello… - Gastroenterology, 2018 - Elsevier
Background & Aims Changes to the microenvironment of pancreatic ductal
adenocarcinomas (PDACs) have been associated with poor outcomes of patients. We …

[HTML][HTML] Liposome-based diagnostic and therapeutic applications for pancreatic cancer

F Raza, L Evans, M Motallebi, H Zafar, M Pereira-Silva… - Acta Biomaterialia, 2023 - Elsevier
Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …

Iron oxide nanoparticles for therapeutic applications

E Alphandéry - Drug discovery today, 2020 - Elsevier
Highlights•IONP therapeutic activity activated by local heat, ROS, drug release.•IONP
activation controllable by the application of an external source of energy.•IONP can be …