Protein-based antigen presentation platforms for nanoparticle vaccines

B Nguyen, NH Tolia - npj Vaccines, 2021 - nature.com
Modern vaccine design has sought a minimalization approach, moving to the isolation of
antigens from pathogens that invoke a strong neutralizing immune response. This approach …

Cancer nanomedicine: from targeted delivery to combination therapy

X Xu, W Ho, X Zhang, N Bertrand… - Trends in molecular …, 2015 - cell.com
The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of
various diseases, including cancer. The unique properties of nanoparticles (NPs), such as …

[HTML][HTML] Nanoparticle vaccines

L Zhao, A Seth, N Wibowo, CX Zhao, N Mitter, C Yu… - Vaccine, 2014 - Elsevier
Nanotechnology increasingly plays a significant role in vaccine development. As vaccine
development orientates toward less immunogenic “minimalist” compositions, formulations …

Recent advances in subunit vaccine carriers

A Vartak, SJ Sucheck - Vaccines, 2016 - mdpi.com
The lower immunogenicity of synthetic subunit antigens, compared to live attenuated
vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that …

Erythrocyte membrane-enveloped polymeric nanoparticles as nanovaccine for induction of antitumor immunity against melanoma

Y Guo, D Wang, Q Song, T Wu, X Zhuang, Y Bao… - ACS …, 2015 - ACS Publications
Cancer immunotherapy is mainly focused on manipulating patient's own immune system to
recognize and destroy cancer cells. Vaccine formulations based on nanotechnology have …

Biomaterials Facilitating Dendritic Cell‐Mediated Cancer Immunotherapy

H Dong, Q Li, Y Zhang, M Ding, Z Teng… - Advanced …, 2023 - Wiley Online Library
Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …

Recent advances in cell membrane‐derived biomimetic nanotechnology for cancer immunotherapy

F Raza, H Zafar, S Zhang, Z Kamal, J Su… - Advanced …, 2021 - Wiley Online Library
Immunotherapy will significantly impact the standard of care in cancer treatment. Recent
advances in nanotechnology can improve the efficacy of cancer immunotherapy. However …

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …

Nanoparticles and vaccine development

M Kheirollahpour, M Mehrabi… - Pharmaceutical …, 2020 - ingentaconnect.com
In spite of the progress of conventional vaccines, improvements are required due to
concerns about the low immunogenicity of the toxicity, instability, and the need for multiple …

Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers

FM Kievit, M Zhang - Advanced materials, 2011 - Wiley Online Library
Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …