Development of structural complexity by liquid‐crystal self‐assembly

C Tschierske - Angewandte Chemie International Edition, 2013 - Wiley Online Library
Since the discovery of the liquid‐crystalline state of matter 125 years ago, this field has
developed into a scientific area with many facets. This Review presents recent …

Mimicking the cell: bio-inspired functions of supramolecular assemblies

Y Tu, F Peng, A Adawy, Y Men… - Chemical …, 2016 - ACS Publications
The successful assembly of large supramolecular structures infers a delicate balance
between reversible noncovalent interactions which are capable of undergoing correction …

From structure to function via complex supramolecular dendrimer systems

HJ Sun, S Zhang, V Percec - Chemical Society Reviews, 2015 - pubs.rsc.org
This tutorial review summarizes strategies elaborated for the discovery and prediction of
programmed primary structures derived from quasi-equivalent constitutional isomeric …

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to …

V Percec, P Leowanawat, HJ Sun… - Journal of the …, 2013 - ACS Publications
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …

Enzyme responsive rigid-rod aromatics target “undruggable” phosphatases to kill cancer cells in a mimetic bone microenvironment

M Yi, F Wang, W Tan, JT Hsieh… - Journal of the …, 2022 - ACS Publications
Bone metastasis remains a challenge in cancer treatment. Here we show enzymatic
responsive rigid-rod aromatics acting as the substrates of “undruggable” phosphatases to …

Helical self-organizations and emerging functions in architectures, biological and synthetic macromolecules

V Percec, Q Xiao - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
Helical architectures including artwork and monuments, such us the Trajan's column from
Rome, were constructed as early as in the year 113 while the assemblies and the self …

Predicting the size and properties of dendrimersomes from the lamellar structure of their amphiphilic Janus dendrimers

M Peterca, V Percec, P Leowanawat… - Journal of the American …, 2011 - ACS Publications
Dendrimersomes are stable, monodisperse unilamellar vesicles self-assembled in water
from amphiphilic Janus dendrimers. Their size, stability, and membrane structure are …

Theoretical modeling and simulations of self-assembly of copolymers in solution

Q Zhang, J Lin, L Wang, Z Xu - Progress in Polymer Science, 2017 - Elsevier
Self-assembly of copolymers in solution is a promising way to prepare novel materials. An
accurate control over the self-assembly of copolymers in solution requires a profound …

Positional isomerism mediated the self-assembly and optical properties of amphiphilic cyanostyrene-based mesogens

N Li, Y Liang, X Liu, G Liang, Q Zhang, R Zhang… - Journal of …, 2023 - Elsevier
Two novel amphiphiles containing phenylthiophene and cyanostyrene group in the rigid
core and a methyl and an oligooxyethylene unit at the terminal were synthesized by Suzuki …

Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers …

J Lu, EN Atochina-Vasserman, DS Maurya, MI Shalihin… - Pharmaceutics, 2023 - mdpi.com
Viral and synthetic vectors to deliver nucleic acids were key to the rapid development of
extraordinarily efficient COVID-19 vaccines. The four-component lipid nanoparticles (LNPs) …