Abstract The Global Burden of Disease report of 2019 estimated 14 million infection‐related
deaths, making it the second leading cause of death after ischaemic heart disease. Bacterial …

Insufficient development of new antibiotics and the rise in antimicrobial resistance are
putting the world at risk of losing curative medicines against bacterial infection. Quorum …

Scalable syntheses of the northern macrobicyclic thiolincosamine fragments of two
structurally complex antibiotic candidates, BT-33 and cresomycin, are presented. A key …

Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are
unable to counter the growing challenge of antibiotic resistance that is conferred by the …

The rapid spread of antimicrobial resistance poses a critical threat to global health and the
environment. Antimicrobial nanomaterials, including silver nanoparticles (AgNPs), are being …

Antibiotic resistance has become a critical health crisis globally. Traditional strategies using
antibiotics can lead to drug-resistance, while inorganic antimicrobial agents can cause …

bis (4-methoxyphenamino) pyrimidines are effective anti-bacterial against various bacteria.
The compounds 1a and 1b displayed IC 50 values of 3 µM and 6.1 µM, respectively, against …

Soil microbial fuel cells (MFCs) can control the horizontal transfer of antibiotic resistance
genes (ARGs) by reducing the abundance of mobile genetic elements. However, little is …

Nonvesicular lipid trafficking pathways are an important process in every domain of life. The
mechanisms of these processes are poorly understood in part due to the difficulty in kinetic …

The progress and growth of drug discovery and development (DDD) in the past five decades
are reviewed in terms of the changing trends over the years. The importance of the …