The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …

Patterned substitution of d-amino acids into the primary sequences of self-assembling
peptides influences molecular-level packing and supramolecular morphology. We report …

Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

Short peptides are poorly immunogenic when delivered sublingually–under the tongue.
Nanomaterial delivery of peptides could be utilized to improve immunogenicity towards …

Nanostructures formed by peptides that self-assemble in water through non-covalent
interactions have attracted considerable attention because peptides possess several unique …

Biomaterials employed to raise therapeutic immune responses have become a complex and
active field. Historically, vaccines have been developed primarily to fight infectious diseases …

Cancer immunotherapy has achieved promising clinical results. However, many limitations
associated with current cancer immunotherapy still exist, including low response rates and …

The binding of clofazimine to human serum albumin (HSA) was investigated by applying
optical spectroscopy and molecular docking methods. Fluorescence quenching data …