Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

Protein palmitoylation, a classical and common lipid modification, regulates diverse aspects
of neuronal protein trafficking and function. The reversible nature of palmitoylation provides …

S-palmitoylation describes the reversible attachment of fatty acids (predominantly palmitate)
onto cysteine residues via a labile thioester bond. This posttranslational modification …

S-palmitoylation is a reversible post-translational modification that occurs on diverse cellular
proteins. Palmitoylation can affect proteins in many different ways, including regulating …

Autosomal-dominant adult-onset neuronal ceroid lipofuscinosis (ANCL) is characterized by
accumulation of autofluorescent storage material in neural tissues and neurodegeneration …

While retrograde cargo selection in the Golgi is known to depend on specific signals, it is
unknown whether anterograde cargo is sorted, and anterograde signals have not been …

S-acylation is a major posttranslational modification, catalyzed by the zinc finger DHHC
domain containing (zDHHC) enzyme family. S-acylated proteins can be modified by different …

Palmitoylation, a key regulatory mechanism controlling protein targeting, is catalyzed by
DHHC-family palmitoyl acyltransferases (PATs). Impaired PAT activity is linked to …