Controlling reactive oxygen species (ROS) at sustainable levels can drive multiple facets of
tumor biology, including within the cancer stem cell (CSC) population. Tight regulation of …

Cancer stem cells (CSCs) have emerged as key contributors to tumor initiation, growth, and
metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby …

The application of nanoarchitectures in cancer therapy seems to be beneficial for the
delivery of anti-tumor drugs. In recent years, attempts have been made to reverse drug …

Cell fusion is involved in many physiological and pathological processes, including gamete
binding, and cancer development. The basic processes of cell fusion include membrane …

Cancer stem cells (CSCs) have been identified and characterized in both hematopoietic and
solid tumors. Their existence was first predicted by Virchow and Cohnheim in the 1870s …

Patient-derived cells and xenografts retain the biological characteristics of clinical cancers
and are instrumental in gaining a better understanding of the chemoresistance of cancer …

Objective. To explore the cancer stemness features and develop a novel cancer stemness‐
related prognostic signature for colon adenocarcinoma (COAD). Methods. We downloaded …

Background Chemoresistance is a main obstacle in gastric cancer (GC) treatment, but its
molecular mechanism still needs to be elucidated. Here, we aim to reveal the underlying …

Aims The potential of all-trans retinoic acid (ATRA) in regulating some microRNAs (miRNAs)
involved in multiple cancer-related pathways, including resistance to chemotherapeutics …

Cancer chemoresistance is often attributed to slow-cycling persister populations with cancer
stem cell (CSC)-like features. However, how persister populations emerge and prevail in …