Oxidative stress, inflammation, and neuroprogression in chronic PTSD

MW Miller, AP Lin, EJ Wolf… - Harvard review of …, 2018 - journals.lww.com
Posttraumatic stress disorder is a serious and often disabling syndrome that develops in
response to a traumatic event. Many individuals who initially develop the disorder go on to …

Inflammation in post-traumatic stress disorder (PTSD): a review of potential correlates of PTSD with a neurological perspective

TD Kim, S Lee, S Yoon - Antioxidants, 2020 - mdpi.com
Post-traumatic stress disorder (PTSD) is a chronic condition characterized by symptoms of
physiological and psychosocial burden. While growing research demonstrated signs of …

Depression and sterile inflammation: essential role of danger associated molecular patterns

TC Franklin, C Xu, RS Duman - Brain, behavior, and immunity, 2018 - Elsevier
Stress is a major risk factor for psychiatric disorder including major depressive disorder
(MDD) and can induce inflammation, which is known to be dysregulated in depression …

Metabolism, metabolomics, and inflammation in posttraumatic stress disorder

SH Mellon, A Gautam, R Hammamieh, M Jett… - Biological …, 2018 - Elsevier
Posttraumatic stress disorder (PTSD) is defined by classic psychological manifestations,
although among the characteristics are significantly increased rates of serious somatic …

Neurophysiology and psychopathology underlying PTSD and recent insights into the PTSD therapies—a comprehensive review

G Aliev, NM Beeraka, VN Nikolenko… - Journal of clinical …, 2020 - mdpi.com
Post-traumatic stress disorder (PTSD) is a well-known psychiatric disorder that affects
millions of people worldwide. Pharmacodynamic and cognitive-behavioral therapies (CBT) …

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation

CE Carey, R Shafee, R Wedow, A Elliott… - Nature Human …, 2024 - nature.com
Data within biobanks capture broad yet detailed indices of human variation, but biobank-
wide insights can be difficult to extract due to complexity and scale. Here, using large-scale …

Involvement of nuclear factor-κB in inflammation and neuronal plasticity associated with post-traumatic stress disorder

S Gupta, RS Guleria - Cells, 2022 - mdpi.com
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition which develops
either due to stress or witnessing a traumatic situation. PTSD is characterized by acute and …

An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders

PF Kuan, MA Waszczuk, R Kotov, CJ Marsit… - Translational …, 2017 - nature.com
Previous epigenome-wide association studies (EWAS) of posttraumatic stress disorder
(PTSD) and major depressive disorder (MDD) have been inconsistent. This may be due to …

C‐reactive protein: Marker of risk for post‐traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery

SF Friend, R Nachnani, SB Powell… - European Journal of …, 2022 - Wiley Online Library
Increasing evidence indicates that inflammation plays a role in PTSD and stress disorder
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …

CRP polymorphisms and DNA methylation of the AIM2 gene influence associations between trauma exposure, PTSD, and C-reactive protein

MW Miller, H Maniates, EJ Wolf, MW Logue… - Brain, behavior, and …, 2018 - Elsevier
Background Recent studies have implicated inflammatory processes in the pathophysiology
of posttraumatic stress disorder (PTSD). C-reactive protein (CRP) is a widely-used measure …