Bronchiolitis

SR Dalziel, L Haskell, S O'Brien, ML Borland, AC Plint… - The Lancet, 2022 - thelancet.com
Viral bronchiolitis is the most common cause of admission to hospital for infants in high-
income countries. Respiratory syncytial virus accounts for 60–80% of bronchiolitis …

UPDATE-2022 Italian guidelines on the management of bronchiolitis in infants

S Manti, A Staiano, L Orfeo, F Midulla… - Italian journal of …, 2023 - Springer
Bronchiolitis is an acute respiratory illness that is the leading cause of hospitalization in
young children. This document aims to update the consensus document published in 2014 …

Nebulised hypertonic saline solution for acute bronchiolitis in infants

L Zhang, RA Mendoza-Sassi… - Cochrane database …, 2023 - cochranelibrary.com
Background Airway oedema (swelling) and mucus plugging are the principal pathological
features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) …

Essentials in saline pharmacology for nasal or respiratory hygiene in times of COVID-19

S Huijghebaert, L Hoste, G Vanham - European journal of clinical …, 2021 - Springer
Purpose Nasal irrigation or nebulizing aerosol of isotonic or hypertonic saline is a traditional
method for respiratory or nasal care. A recent small study in outpatients with COVID-19 …

Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children

XL Zhang, X Zhang, W Hua, ZD Xie, HM Liu… - World Journal of …, 2024 - Springer
Background Respiratory syncytial virus (RSV) is the leading global cause of respiratory
infections and is responsible for about 3 million hospitalizations and more than 100,000 …

3% nebulized hypertonic saline versus normal saline for infants with acute bronchiolitis: A systematic review and meta-analysis of randomized controlled trials

JF Yu, Y Zhang, ZB Liu, J Wang, LP Bai - Medicine, 2022 - journals.lww.com
Background: This study evaluated the efficacy and safety of 3% nebulized hypertonic saline
(NHS) in infants with acute bronchiolitis (AB). Methods: We systematically searched the …

Bronchiolitis: from practice guideline to clinical practice

M Kou, V Hwang… - Emergency Medicine …, 2018 - emed.theclinics.com
This article discusses recent literature to inform the implementation of the American
Academy of Pediatrics'(AAP's) bronchiolitis clinical practice guideline (CPG) into the …

Evaluating the placebo status of nebulized normal saline in patients with acute viral bronchiolitis: a systematic review and meta-analysis

SA House, AM Gadomski, SL Ralston - JAMA pediatrics, 2020 - jamanetwork.com
Importance In therapeutic trials for acute viral bronchiolitis, consistent clinical improvement
in groups that received nebulized normal saline (NS) as placebo raises the question of …

Cytokine–ion channel interactions in pulmonary inflammation

J Hamacher, Y Hadizamani, M Borgmann… - Frontiers in …, 2018 - frontiersin.org
The lungs conceptually represent a sponge that is interposed in series in the bodies'
systemic circulation to take up oxygen and eliminate carbon dioxide. As such, it matches the …

Exploring the efficacy of using hypertonic saline for nebulizing treatment in children with bronchiolitis: a meta-analysis of randomized controlled trials

CW Hsieh, C Chen, HC Su, KH Chen - BMC pediatrics, 2020 - Springer
Background Inhaled hypertonic saline (HS) has shown benefit in decreasing airway edema
in acute bronchiolitis which is the most common lower respiratory infection resulting in …