Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …

A typical output of a metabolomic experiment is a peak table corresponding to the intensity
of measured signals. Peak table processing, an essential procedure in metabolomics, is …

Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

The successful treatment of osteomyelitis remains a great challenge in the field of
orthopedics. The clinical method for treating refractory bone infection requires a combination …

The rising prevalence of multidrug-resistant bacteria is an urgent health crisis that can only
be countered through renewed investment in the discovery and development of antibiotics …

Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Berberine hydrochloride (BBR) is a natural product widely used in clinical medicine and
animal production. It has a variety of antimicrobial effects, but its complex antimicrobial …

The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …

Protocatechuic acid (PCA) has adequate antibacterial activity against foodborne pathogens;
however, its antibacterial mechanism has been rarely investigated. Therefore, this study …

Antimicrobial resistance (AMR), the ability of bacterial species to develop resistance against
exposed antibiotics, has gained immense global attention in the past few years. Bacterial …