Microtubules are non-covalent mesoscale polymers central to the eukaryotic cytoskeleton.
Microtubule structure, dynamics, and mechanics are modulated by a cell's choice of tubulin …

Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to
and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more …

The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

Natural compounds that target microtubules and disrupt the normal function of the mitotic
spindle have proven to be one of the best classes of cancer chemotherapeutic drugs …

Half a century of biochemical and biophysical experiments has provided attractive models
that may explain the diverse functions of microtubules within cells and organisms. However …

Polyploidization of plants occurs in nature but it is a slow and gradual process that has
driven evolution and speciation throughout the ages. As time is important, polyploidization …

Microtubules have long been considered an ideal target for anticancer drugs because of the
essential role they play in mitosis, forming the dynamic spindle apparatus. As such, there is …

Microtubules, major structural components in cells, are the target of a large and diverse
group of natural product anticancer drugs. Given the success of this class of drugs in cancer …

Intracellular recordings were obtained from directly identified rat nigral dopamine cells in
vivo. This identification was based on an increase in glyoxylic acid-induced catecholamine …

Many diseases have been described to be associated with inflammatory processes. The
currently available anti‐inflammatory drug therapy is often not successful or causes …