Current approaches to the management of brain metastases

JH Suh, R Kotecha, ST Chao, MS Ahluwalia… - Nature reviews Clinical …, 2020 - nature.com
Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma

E Hasanov, DN Yeboa, MD Tucker… - CA: A Cancer …, 2022 - Wiley Online Library
Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited
understanding of brain metastasis tumor and immune biology, drivers of resistance to …

Preoperative versus postoperative radiosurgery of brain metastases: a meta-analysis

R Dharnipragada, K Dusenbery, C Ferreira… - World neurosurgery, 2024 - Elsevier
Objective While postoperative resection cavity radiosurgery (post-SRS) is an accepted
treatment paradigm for brain metastasis (BM) patients who undergo surgical resection, there …

Medical management of brain metastases

A Lauko, Y Rauf, MS Ahluwalia - Neuro-Oncology Advances, 2020 - academic.oup.com
The development of brain metastases occurs in 10–20% of all patients with cancer. Brain
metastases portend poor survival and contribute to increased cancer mortality and morbidity …

Integration of systemic therapy and stereotactic radiosurgery for brain metastases

R Tonse, MC Tom, MP Mehta, MS Ahluwalia… - Cancers, 2021 - mdpi.com
Simple Summary In the multi-modal treatment of brain metastasis (BM), the role of systemic
therapy has undergone a recent revolution. Due to the development of multiple agents with …

Fatty acid synthase: a druggable driver of breast cancer brain metastasis

JA Menendez, R Lupu - Expert opinion on therapeutic targets, 2022 - Taylor & Francis
ABSTRACT Introduction Brain metastasis (BrM) is a key contributor to morbidity and
mortality in breast cancer patients, especially among high-risk epidermal growth factor …

Opportunities and alternatives of modern radiation oncology and surgery for the management of resectable brain metastases

CD Diehl, FA Giordano, AL Grosu, S Ille, KH Kahl… - Cancers, 2023 - mdpi.com
Simple Summary Brain metastases are of increasing concern in the management of cancer
patients. New systemic treatment options like specific targeting agents or immune …

Novel strategies for nanoparticle-based radiosensitization in glioblastoma

H Ruiz-Garcia, C Ramirez-Loera, TD Malouff… - International journal of …, 2021 - mdpi.com
Radiotherapy (RT) is one of the cornerstones in the current treatment paradigm for
glioblastoma (GBM). However, little has changed in the management of GBM since the …

Leptomeningeal disease in glioblastoma: endgame or opportunity?

S Akmal, EE Ginalis, NV Patel, R Aiken… - Journal of Neuro …, 2021 - Springer
Introduction Glioblastoma is an aggressive cancer with a notoriously poor prognosis. Recent
advances in treatment have increased overall survival, though this may be accompanied by …

Brain metastases: An update on the multi-disciplinary approach of clinical management

DK Mitchell, HJ Kwon, PA Kubica, WX Huff, R O'regan… - Neurochirurgie, 2022 - Elsevier
Importance Brain metastasis (BM) is the most common malignant intracranial neoplasm in
adults with over 100,000 new cases annually in the United States and outnumbering primary …