Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission

CN Roy, ST Shu, C Kline, L Rigatti, TE Smithgall… - Scientific Reports, 2023 - nature.com
Humanized mice have been used to study human immunodeficiency virus type 1 (HIV-1)
transmission, pathogenesis, and treatment. The ability of pediatric thymus tissue implanted …

Highly Sensitive Analysis of Cervical Mucosal HIV-1 Infection Using Reporter Viruses Expressing Secreted Nanoluciferase

DF Indihar, JJ Jones, C Ochsenbauer, JC Kappes - HIV Protocols, 2024 - Springer
Ex vivo cervical tissue explant models offer a physiologically relevant approach for studying
virus-host interactions that underlie mucosal HIV-1 transmission to women. However, the …

Visualizing lymphocytic choriomeningitis virus infection in cells and living mice

Y Wen, H Xu, W Wan, W Shang, R Jin, F Zhou, H Mei… - Iscience, 2022 - cell.com
Mammarenavirus are a large family of enveloped negative-strand RNA viruses that include
several agents responsible for severe hemorrhagic fevers. Until now, no FDA-licensed drug …

[PDF][PDF] Étude de l'implication des microglies dans la pathogenèse de l'encéphalite herpétique expérimentale

O Uyar - 2022 - core.ac.uk
Résumé Les infections au virus herpès simplex I (VHS-1) sont souvent bénignes mais
peuvent être responsables de pathologies sévères, telle que l'infection du système nerveux …