Microelectrode arrays (MEAs) have been in use over the past decade and a half to study
multiple aspects of electrically excitable cells. In particular, MEAs have been applied to …

Great progress has been made over the past 40 years in understanding the hazards of
exposure to a small number of developmental neurotoxicants. Lead, polychlorinated …

There is a worldwide concern on adverse health effects of dietary exposure to acrylamide
(AA) due to its presence in commonly consumed foods. AA is formed when carbohydrate …

There is a critical need for strategies that effectively enhance cell viability and post-
implantation performance in order to advance cell-based therapies. Spheroids, which are …

In vitro, high-throughput methods have been widely recommended as an approach to
screen chemicals for the potential to cause developmental neurotoxicity and prioritize them …

Because the Developmental Neurotoxicity Testing Guidelines require large numbers of
animals and is expensive, development of in vitro approaches to screen chemicals for …

There is a need to develop rapid and efficient models to screen chemicals for their potential
to cause developmental neurotoxicity. Use of in vitro neuronal models, including human …

Object Seizures in the perioperative period are a well-recognized clinical entity in the setting
of brain tumor surgery. At present, the suitability of antiepileptic prophylaxis in patients …

Developmental neurotoxicity (DNT) is an important endpoint for the safety assessment of
chemicals. However, the current in vivo animal model for DNT assessment is resource …

The nervous system has a highly complex organization, including many cell types with
multiple functions, with an intricate anatomy and unique structural and functional …