Acinetobacter baumannii: an evolving and cunning opponent

J Shi, J Cheng, S Liu, Y Zhu, M Zhu - Frontiers in Microbiology, 2024 - frontiersin.org
Acinetobacter baumannii is one of the most common multidrug-resistant pathogens causing
nosocomial infections. The prevalence of multidrug-resistant A. baumannii infections is …

Antimicrobial resistance: two-component regulatory systems and multidrug efflux pumps

GV De Gaetano, G Lentini, A Famà, F Coppolino… - Antibiotics, 2023 - mdpi.com
The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the
various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps …

The multifaceted genus Acinetobacter: from infection to bioremediation

U Dahal, K Paul, S Gupta - Journal of Applied Microbiology, 2023 - academic.oup.com
Acinetobacter is a vast bacterial genus comprising of numerous species with variable
characteristics. The enigma associated with clinical strains that have been implicated in …

Pan-Genome Plasticity and Virulence Factors: A Natural Treasure Trove for Acinetobacter baumannii

T Karampatakis, K Tsergouli, P Behzadi - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii is a Gram-negative pathogen responsible for a variety of
community-and hospital-acquired infections. It is recognized as a life-threatening pathogen …

Characterization of pyridylpiperazine-based efflux pump inhibitors for Acinetobacter baumannii

JC Jiménez-Castellanos, E Pradel… - JAC-Antimicrobial …, 2023 - academic.oup.com
Abstract Objectives In Acinetobacter baumannii, multidrug efflux pumps belonging to the
resistance-nodulation-division (RND) superfamily result in decreased antibiotic …

Phylogenomic and phenotypic analyses highlight the diversity of antibiotic resistance and virulence in both human and non-human Acinetobacter baumannii

EME Sykes, V Mateo-Estrada, R Engelberg… - Msphere, 2024 - Am Soc Microbiol
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes infections
in the immunocompromised. With a high incidence of muti-drug resistance, carbapenem …

Differential development of antibiotic resistance and virulence between Acinetobacter species

EM Darby, RA Moran, E Holden, T Morris, F Harrison… - Msphere, 2024 - Am Soc Microbiol
The two species that account for most cases of Acinetobacter-associated bacteremia in the
United Kingdom are Acinetobacter lwoffii, often a commensal but also an emerging …

[HTML][HTML] Genome-wide sRNA and mRNA transcriptomic profiling insights into carbapenem-resistant Acinetobacter baumannii

Y Wei, X Xin, J Zhang, Q Liao, Y Rong… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction: Acinetobacter baumannii (AB) is rising as a human pathogen of critical priority
worldwide as it is the leading cause of opportunistic infections in healthcare settings and …

Three novel multiplex PCR assays for rapid detection of virulence, antimicrobial resistance, and toxin genes in Acinetobacter calcoaceticus-baumannii complex …

AA Sheikh, D Schneiderman, EME Sykes… - Letters in Applied …, 2024 - academic.oup.com
The Acinetobacter calcoaceticus-baumannii (ACB) complex is an often-overlooked group of
nosocomial pathogens with a significant environmental presence. Rapid molecular …

Types and Mechanisms of Efflux Pump Systems and the Potential of Efflux Pump Inhibitors in the Restoration of Antimicrobial Susceptibility, with a Special Reference …

KM Zack, T Sorenson, SG Joshi - Pathogens, 2024 - mdpi.com
Bacteria express a plethora of efflux pumps that can transport structurally varied molecules,
including antimicrobial agents and antibiotics, out of cells. Thus, efflux pump systems …