An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

Childhood maltreatment has been suggested to have an adverse impact on
neurodevelopment, including microstructural brain abnormalities. Existing neuroimaging …

Early life stress (ELS) is a well-established risk factor for many psychiatric and medical
disorders, including substance use disorders (SUDs). The relationship between ELS and …

We conducted the first meta-analysis of whole-brain voxel-based DTI studies in childhood
maltreatment to elucidate regions of white matter (WM) microstructure abnormality relative to …

BackgroundChildhood maltreatment (CM) plays an important role in the development of
major depressive disorder (MDD). The aim of this study was to examine whether CM severity …

Childhood trauma, and in particular physical neglect, has been repeatedly associated with
lower performance on measures of social cognition (eg emotion recognition tasks) in both …

Stress-related psychiatric conditions are one of the main causes of disability in developed
countries. They account for a large portion of resource investment in stress-related …

The developing brain is marked by high plasticity, which can lead to vulnerability to early life
stressors. Previous studies indicate that childhood maltreatment is associated with structural …