Parkinson's disease causes a characteristic combination of motor symptoms due to
progressive neurodegeneration of dopaminergic neurons in the substantia nigra pars …

Currently, neurodegenerative diseases are a major cause of disability around the world.
Parkinson's disease (PD) is the second-leading cause of neurodegenerative disorder after …

Human performance, endurance, and resilience have biological limits that are genetically
and epigenetically predetermined but perhaps not yet optimized. There are few systematic …

Patients with Parkinson's disease (PD) show impaired short-term potentiation (STP)
mechanisms in the primary motor cortex (M1). However, the role played by this …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the
degeneration of dopaminergic neurons and/or loss od neuronal projections, in several …

Movement disorders arise from the complex interplay of multiple changes to neural circuits.
Successful treatments for these disorders could interact with these complex changes in …

Animals live in habitats fraught with a range of environmental challenges to their bodies and
brains. Accordingly, cells and organ systems have evolved stress-responsive signaling …

The basal ganglia represent an ancient part of the nervous system that have remained
organized in a similar way over the last 500 million years and are of importance for our …

Aims To develop an automatic method of classification for parkinsonian variant of multiple
system atrophy (MSA‐P) and Idiopathic Parkinson's disease (IPD) in early to moderately …

Increasing evidence suggest that excessive inflammatory responses from overactivated
microglia play a critical role in Parkinson's disease (PD), contributing to, or exacerbating …