Tumor-derived extracellular vesicles: The metastatic organotropism drivers

J Rezaie, M Ahmadi, R Ravanbakhsh, B Mojarad… - Life Sciences, 2022 - Elsevier
The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …

Engineered extracellular vesicles: A novel platform for cancer combination therapy and cancer immunotherapy

M Ahmadi, M Hassanpour, J Rezaie - Life Sciences, 2022 - Elsevier
Extracellular vesicles (EVs), phospholipid membrane-bound vesicles, produced by most
cells, contribute to cell-cell communication. They transfer several proteins, lipids, and nucleic …

Tumor cells‐derived exosomal noncoding RNAs in cancer angiogenesis: Molecular mechanisms and prospective

F Nazari‐Khanamiri, N Abdyazdani… - Cell Biochemistry …, 2023 - Wiley Online Library
Exosomes, heterogeneous, membrane‐bound nanoparticles that originated from eukaryotic
cells, contribute to intracellular communication by transferring various biomolecules both on …

Crocin attenuates inflammation of lung tissue in ovalbumin‐sensitized mice by altering the expression of endoplasmic reticulum stress markers

MR Aslani, M Amani, N Masrori, MH Boskabady… - Biofactors, 2022 - Wiley Online Library
Endoplasmic reticulum (ER) stress plays a pivotal role in the pathogenesis of asthma. The
present study aimed to investigate the reducing or suppressing effects of crocin in ovalbumin …

Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer

R Abbasi, RM Mesgin, F Nazari-Khanamiri… - European Journal of …, 2023 - Springer
Background The advancement in novel cancer therapeutics brought a platform combining
the properties of exosomes with nanoparticles to precision medicine. The novel therapeutic …

Altered gene expression levels of IL-17/TRAF6/MAPK/USP25 axis and pro-inflammatory cytokine levels in lung tissue of obese ovalbumin-sensitized rats

MR Aslani, A Sharghi, MH Boskabady, H Ghobadi… - Life Sciences, 2022 - Elsevier
Aims The association between asthma and obesity has been shown but its accurate
mechanism is unknown. In the current study, we sought to investigate the gene expression …

Recent advances in mechanistic studies of heart failure with preserved ejection fraction and its comorbidities—Role of microRNAs

X Li, M Sun, Z Wang, S Sun… - European Journal of …, 2024 - Wiley Online Library
Background Heart failure with preserved ejection fraction (HFpEF) is a multifaceted
syndrome with a complex aetiology commonly associated with comorbidities such as …

[HTML][HTML] Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice

MR Aslani, Z Jafari, R Rahbarghazi… - Iranian journal of …, 2022 - ncbi.nlm.nih.gov
Objective (s): Although various studies have revealed the beneficial effects of crocin (derived
from saffron), such as anti-inflammatory, anti-cancer, antioxidant, and immune modulator …

Modification of lung endoplasmic reticulum genes expression and NF-kB protein levels in obese ovalbumin-sensitized male and female rats

MR Aslani, H Ghobadi, H Panahpour, M Ahmadi… - Life sciences, 2020 - Elsevier
Aims Previous studies showed a close relationship between obesity and asthma. In this
study, we investigated the expression of endoplasmic reticulum (ER) stress genes in the …

Adipolin and IL-6 serum levels in chronic obstructive pulmonary disease

MR Aslani, M Amani, F Moghadas… - Advances in Respiratory …, 2022 - mdpi.com
Highlights What are the main findings? This study showed reduced adipolin serum levels as
a pro-inflammatory molecule in COPD patients. Serum adipolin levels correlate with serum …