Peptides are emerging as a new reliable class of therapeutics and, thanks to their lower cost of production, they are becoming established as perfect drug aspirants. Here, we briefly …
J Paczesny, K Bielec - Nanomaterials, 2020 - mdpi.com
Bacteriophages (phages for short) are viruses, which have bacteria as hosts. The single phage body virion, is a colloidal particle, often possessing a dipole moment. As such …
M Weichseldorfer, M Reitz, OS Latinovic - Pharmaceutics, 2021 - mdpi.com
Combined antiretroviral therapy (cART) is treatment with a combination of several antiretroviral drugs that block multiple stages in the virus replication cycle. An estimated 60 …
Tumor-derived exosomes (TDEs) play a pivotal role in tumor establishment and progression, and are emerging biomarkers for tumor diagnosis in personalized medicine. To date, there …
M Pontoriero, G Fiume, E Vecchio… - Journal of Molecular …, 2019 - Springer
The antigen-mediated triggering of B cell receptor (BCR) activates the transcription factor NF- κB that regulates the expression of genes involved in B cell differentiation, proliferation, and …
The pharmaceutical use of bacteriophages as safe and inexpensive therapeutic tools is collecting renewed interest. The use of lytic phages to fight antibiotic-resistant bacterial …
E Vecchio, C Caiazza, S Mimmi, A Avagliano… - Frontiers in Cell and …, 2021 - frontiersin.org
Tumor interstitial fluid (TIF) surrounds and perfuses tumors and collects ions, metabolites, proteins, and extracellular vesicles secreted by tumor and stromal cells. Specific …
N Nisticò, D Maisano, E Iaccino, E Vecchio, G Fiume… - Pharmaceuticals, 2020 - mdpi.com
Chronic lymphocytic leukemia (CLL) is a B-lymphoproliferative disease, which consists of the abnormal proliferation of CD19/CD5/CD20/CD23 positive lymphocytes in blood and …
Vaccines represent the most relevant contribution of immunology to human health. However, despite the remarkable success achieved in the past years, many vaccines are still missing …