Frailty and cancer: current perspectives on assessment and monitoring

V Goede - Clinical interventions in aging, 2023 - Taylor & Francis
Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

Practical assessment and management of vulnerabilities in older patients receiving systemic cancer therapy: ASCO guideline update

W Dale, HD Klepin, GR Williams… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To update the ASCO guideline (2018) on the practical assessment and
management of age-associated vulnerabilities in older patients undergoing systemic cancer …

The effect of comprehensive geriatric assessment on care received, treatment completion, toxicity, cancer-related and geriatric assessment outcomes, and quality of …

D Disalvo, E Moth, WK Soo, MV Garcia… - Journal of Geriatric …, 2023 - Elsevier
Introduction This systematic review aims to summarise the available literature on the effect of
geriatric assessment (multidimensional health assessment across medical, social, and …

Geriatric assessment and management: is decreasing treatment toxicity good enough?

KP Loh, SG Mohile - JNCI: Journal of the National Cancer …, 2023 - academic.oup.com
The majority of new cancer cases occur in older adults. Geriatric assessment and
management (or comprehensive geriatric assessment) refers to the use of various validated …

[HTML][HTML] How representative are participants in geriatric oncology clinical trials? The case of the 5C RCT in geriatric oncology: A cross-sectional comparison to a …

MH Habib, SMH Alibhai, M Puts - Journal of Geriatric Oncology, 2024 - Elsevier
Introduction Frail older adults make up a substantial portion of the older adult population.
However, frail patients are often excluded from randomized controlled trials. This …

Accelerated Aging in Cancer Survivors: Cellular Senescence, Frailty, and Possible Opportunities for Interventions

S Wang, N El Jurdi, B Thyagarajan, A Prizment… - International journal of …, 2024 - mdpi.com
The population of cancer survivors has markedly increased due to the rapid improvements
in cancer treatment. However, cancer survivors experience accelerated aging, which leads …

[HTML][HTML] Significance of the comprehensive geriatric assessment in the administration of chemotherapy to older adults with cancer: Recommendations by the …

K Ninomiya, D Inoue, K Sugimoto, C Tanaka… - Journal of Geriatric …, 2023 - Elsevier
Introduction The number of older patients with cancer is expected to continue to increase
owing to the aging population. Recently, the usefulness of geriatric assessment (GA) …

Association between Computed Tomography-Determined Loss of Muscle Mass and Impaired Three-Month Survival in Frail Older Adults with Cancer

A Tolonen, H Kerminen, K Lehtomäki, H Huhtala… - Cancers, 2023 - mdpi.com
Simple Summary A large proportion of older adults are not fit for oncological treatments due
to frailty and comorbidities. To aid in the decision-making of whom to provide active …

[HTML][HTML] Effect of comprehensive geriatric assessment on hospitalizations in older adults with frailty initiating curatively intended oncologic treatment: The PROGNOSIS …

AKW Giger, HM Ditzel, M Ewertz, H Ditzel… - Journal of Geriatric …, 2024 - Elsevier
Introduction Frailty constitutes a risk for unplanned hospitalizations in older adults with
cancer. This study examines whether comprehensive geriatric assessment (CGA) as an add …

[HTML][HTML] Delivering patient-centered care: outcomes of comprehensive geriatric assessment across healthcare settings

MFB Roma, NIB Garção, KE Covinsky… - … Gerontology and Aging, 2022 - ggaging.com
Comprehensive geriatric assessment (CGA) is a systematic multidimensional and
interdisciplinary evaluation that enables clinicians to recognize age-related impairments and …