Role of Glial Cells in Neuronal Function, Mood Disorders, and Drug Addiction

Y Tizabi, B Getachew, SR Hauser, V Tsytsarev… - Brain Sciences, 2024 - mdpi.com
Mood disorders and substance use disorder (SUD) are of immense medical and social
concern. Although significant progress on neuronal involvement in mood and reward …

Chronic Astrocytic TNFα Production in the Preoptic-Basal Forebrain Causes Aging-like Sleep–Wake Disturbances in Young Mice

A Kostin, MA Alam, A Saevskiy, MN Alam - Cells, 2024 - mdpi.com
Sleep disruption is a frequent problem of advancing age, often accompanied by low-grade
chronic central and peripheral inflammation. We examined whether chronic …

Enhanced Synaptic Inhibition in the Dorsolateral Geniculate Nucleus in a Mouse Model of Glaucoma

MJ Van Hook, S McCool - eneuro, 2024 - eneuro.org
Elevated intraocular pressure (IOP) triggers glaucoma by damaging the output neurons of
the retina called retinal ganglion cells (RGCs). This leads to the loss of RGC signaling to …

Heavy Metals Interactions with Neuroglia and Gut Microbiota: Implications for Huntington's Disease

Y Tizabi, S Bennani, N El Kouhen, B Getachew… - 2024 - preprints.org
Huntington's disease (HD) is a rare but progressive and devastating neurodegenerative
disease characterized by involuntary movements, cognitive decline, executive dysfunction …

A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

HJ Kwon, D Santhosh, Z Huang - bioRxiv, 2024 - biorxiv.org
Amyloid β (Aβ) forms aggregates in the Alzheimer's disease brain and is well known for its
pathological roles. Recent studies show that it also regulates neuronal physiology in the …

Role of Glial Cells in Depression and Drug Addiction

Y Tizabi, B Getachew, SR Hauser, V Tsytsarev… - 2024 - preprints.org
Major depressive disorder (MDD) and substance use disorder (SUD) are of immense
medical and social concerns. Although significant progress on neuronal involvement in …