The human intestinal microbiota is a highly intricate structure with a crucial role in promoting
health and preventing disease. It consists of diverse microbial communities that inhabit the …

Chronic kidney disease (CKD) is a worldwide health problem, because it is one of the most
common complications of metabolic diseases including obesity and type 2 diabetes …

The origin of most bacterial infections in the urinary tract is often presumed to be the gut.
Herein, we investigate the relationship between the gut microbiota and future development …

Renal transplantation is life-changing in many aspects. This includes changes to the gut
microbiome likely due to exposure to immunosuppressive drugs and antibiotics. As a …

Tacrolimus exhibits low and variable drug exposure after oral dosing, but the contributing
factors remain unclear. Based on our recent report showing a positive correlation between …

Gastrointestinal complications are common after renal transplantation, and they have a wide
clinical spectrum, varying from diarrhoea to post-transplant inflammatory bowel disease …

Clinical use of tacrolimus (TAC), an essential immunosuppressant following transplantation,
is complexified by its high pharmacokinetic (PK) variability. The gut microbiota gains …

During the past decades, the gut microbiome emerged as a key player in kidney disease.
Dysbiosis-related uremic toxins together with pro-inflammatory mediators are the main …

Background The gut microbiome is being associated increasingly with development of
infections besides Clostridium difficile infection. A recent study found an association …

BACKGROUND Alopecia areata is a hair loss disease associated with genetics,
autoimmunity, and other factors. There is an intriguing link between alopecia areata and gut …