Innate immunity in vertebrates: an overview

M Riera Romo, D Pérez‐Martínez… - …, 2016 - Wiley Online Library
Innate immunity is a semi‐specific and widely distributed form of immunity, which represents
the first line of defence against pathogens. This type of immunity is critical to maintain …

Toll-like receptors (TLRs) in aquatic animals: signaling pathways, expressions and immune responses

PR Rauta, M Samanta, HR Dash, B Nayak, S Das - Immunology Letters, 2014 - Elsevier
The innate system's recognition of non-self and danger signals is mediated by a limited
number of germ-line encoded pattern recognition receptors (PRRs) that recognize pathogen …

Toll-like receptor signaling in bony fish

A Rebl, T Goldammer, HM Seyfert - Veterinary immunology and …, 2010 - Elsevier
The innate immune system constitutes an efficient defense against invading microbial
pathogens. Toll-like receptors (TLRs) eventually alert vertebrates about the presence of …

Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases

B Novoa, A Figueras - Current topics in innate immunity II, 2012 - Springer
The zebrafish (Danio rerio) has been extensively used in biomedical research as a model to
study vertebrate development and hematopoiesis and recently, it has been adopted into …

Fish immunity and parasite infections: from innate immunity to immunoprophylactic prospects

P Alvarez-Pellitero - Veterinary immunology and immunopathology, 2008 - Elsevier
The increasing economic importance of fish parasitoses for aquaculture and fisheries has
enhanced the interest in the defence mechanisms against these infections. Both innate and …

Mechanisms of fish macrophage antimicrobial immunity

L Grayfer, B Kerimoglu, A Yaparla… - Frontiers in …, 2018 - frontiersin.org
Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …

Aeromonas hydrophila induces intestinal inflammation in grass carp (Ctenopharyngodon idella): An experimental model

X Song, J Zhao, Y Bo, Z Liu, K Wu, C Gong - Aquaculture, 2014 - Elsevier
Bacterial enteritis is a widespread inflammatory disease in most farmed fish, yet its
pathogenesis is largely unknown, primarily because of the paucity of reproducible …

Host-pathogen interactions made transparent with the zebrafish model

AH Meijer, HP Spaink - Current drug targets, 2011 - ingentaconnect.com
The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …

Immunology and zebrafish: spawning new models of human disease

ND Meeker, NS Trede - Developmental & Comparative Immunology, 2008 - Elsevier
The zebrafish has emerged as a powerful new vertebrate model of human disease. Initially
prominent in developmental biology, the zebrafish has now been adopted into varied fields …

Zebrafish as a model for infectious disease and immune function

C Sullivan, CH Kim - Fish & shellfish immunology, 2008 - Elsevier
The zebrafish, Danio rerio, has come to the forefront of biomedical research as a powerful
model for the study of development, neurobiology, and genetics of humans. In recent years …