[HTML][HTML] Collagen type XI alpha 1 (COL11A1): a novel biomarker and a key player in cancer

S Nallanthighal, JP Heiserman, DJ Cheon - Cancers, 2021 - mdpi.com
Simple Summary Collagen type XI alpha 1 (COL11A1) is a part of type XI collagen, which is
important for bone development. Interestingly, COL11A1 levels are frequently upregulated in …

COL11A1/(pro)collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression

F Vázquez-Villa, M García-Ocaña, JA Galván… - Tumor Biology, 2015 - Springer
The COL11A1 human gene codes for the α1 chain of procollagen 11A1 and mature
collagen 11A1, an extracellular minor fibrillar collagen. Under regular conditions, this gene …

[HTML][HTML] A core matrisome gene signature predicts cancer outcome

AE Yuzhalin, T Urbonas, MA Silva, RJ Muschel… - British journal of …, 2018 - nature.com
Background: Accumulating evidence implicates the tumour stroma as an important
determinant of cancer progression but the protein constituents relevant for this effect are …

[HTML][HTML] Insight on colorectal carcinoma infiltration by studying perilesional extracellular matrix

M Nebuloni, L Albarello, A Andolfo, C Magagnotti… - Scientific reports, 2016 - nature.com
The extracellular matrix (ECM) from perilesional and colorectal carcinoma (CRC), but not
healthy colon, sustains proliferation and invasion of tumor cells. We investigated the …

Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer

NPM Brouwer, L Webbink, TS Haddad… - The Journal of …, 2023 - Wiley Online Library
Both lymph node metastases (LNMs) and tumour deposits (TDs) are included in colorectal
cancer (CRC) staging, although knowledge regarding their biological background is lacking …

Collagen XI alpha 1 chain, a potential therapeutic target for cancer

Z Liu, J Lai, H Jiang, C Ma, H Huang - The FASEB Journal, 2021 - Wiley Online Library
Extracellular matrix (ECM) plays an important role in the progression of cancer. Collagen is
the most abundant component in ECM, and it is involved in the biological formation of …

[HTML][HTML] Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated …

K Zhu, L Cai, C Cui, JR de Los Toyos… - PLoS computational …, 2021 - journals.plos.org
During the last ten years, many research results have been referring to a particular type of
cancer-associated fibroblasts associated with poor prognosis, invasiveness, metastasis and …

[HTML][HTML] Collagen XI alpha 1 chain, a novel therapeutic target for cancer treatment

YH Wu, CY Chou - Frontiers in Oncology, 2022 - frontiersin.org
The extracellular matrix (ECM) plays an important role in the progression of cancer.
Collagen is the most abundant component in ECM, and is involved in the biological …

[HTML][HTML] COL11A1 serves as a biomarker for poor prognosis and correlates with immune infiltration in breast cancer

Q Luo, J Li, X Su, Q Tan, F Zhou, S Xie - Frontiers in Genetics, 2022 - frontiersin.org
Breast cancer is the malignant tumor with the highest incidence rate at present, and its
incidence rate ranks first in the female population. COL11A1 is an important component of …

The prognostic significance of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

H Park, Y Lee, H Lee, JW Kim, JH Hwang… - Tumor …, 2017 - journals.sagepub.com
Cancer-associated fibroblasts are abundant in the desmoplastic stroma of pancreatic ductal
adenocarcinomas and are considered to play important roles in tumor progression. In this …