[HTML][HTML] Structural basis of torque generation in the bi-directional bacterial flagellar motor

H Hu, M Santiveri, N Wadhwa, HC Berg… - Trends in biochemical …, 2022 - cell.com
The flagellar stator unit is an oligomeric complex of two membrane proteins (MotA 5 B 2) that
powers bi-directional rotation of the bacterial flagellum. Harnessing the ion motive force …

[HTML][HTML] A new class of biological ion-driven rotary molecular motors with 5: 2 symmetry

M Rieu, R Krutyholowa, NMI Taylor… - Frontiers in …, 2022 - frontiersin.org
Several new structures of three types of protein complexes, obtained by cryo-electron
microscopy (cryo-EM) and published between 2019 and 2021, identify a new family of …

[HTML][HTML] Structure and function of stator units of the bacterial flagellar motor

M Santiveri, A Roa-Eguiara, C Kühne, N Wadhwa… - Cell, 2020 - cell.com
Many bacteria use the flagellum for locomotion and chemotaxis. Its bidirectional rotation is
driven by a membrane-embedded motor, which uses energy from the transmembrane ion …

Molecular mechanism for rotational switching of the bacterial flagellar motor

Y Chang, K Zhang, BL Carroll, X Zhao… - Nature structural & …, 2020 - nature.com
The bacterial flagellar motor can rotate in counterclockwise (CCW) or clockwise (CW)
senses, and transitions are controlled by the phosphorylated form of the response regulator …

FliL ring enhances the function of periplasmic flagella

S Guo, H Xu, Y Chang… - Proceedings of the …, 2022 - National Acad Sciences
Bacterial flagellar motors are rotary machines that can power motility in various fluid and
surface environments, including within hosts. Activation of the stator complex MotA/MotB is …

[HTML][HTML] Structural conservation and adaptation of the bacterial flagella motor

BL Carroll, J Liu - Biomolecules, 2020 - mdpi.com
Many bacteria require flagella for the ability to move, survive, and cause infection. The
flagellum is a complex nanomachine that has evolved to increase the fitness of each …

[HTML][HTML] 3D cryo-EM imaging of bacterial flagella: Novel structural and mechanistic insights into cell motility

S Mondino, F San Martin, A Buschiazzo - Journal of Biological Chemistry, 2022 - ASBMB
Bacterial flagella are nanomachines that enable cells to move at high speeds. Comprising
25 and more different types of proteins, the flagellum is a large supramolecular assembly …

Mechanosensitive remodeling of the bacterial flagellar motor is independent of direction of rotation

N Wadhwa, Y Tu, HC Berg - Proceedings of the National …, 2021 - National Acad Sciences
Motility is important for the survival and dispersal of many bacteria, and it often plays a role
during infections. Regulation of bacterial motility by chemical stimuli is well studied, but …

Novel transient cytoplasmic rings stabilize assembling bacterial flagellar motors

M Kaplan, CM Oikonomou, CR Wood, G Chreifi… - The EMBO …, 2022 - embopress.org
The process by which bacterial cells build their intricate flagellar motility apparatuses has
long fascinated scientists. Our understanding of this process comes mainly from studies of …

The contributions of fliG gene to the pathogenicity of Pseudomonas plecoglossicida and pathogen-host interactions with Epinephelus coioides

J Jiao, L Zhao, L Huang, Y Qin, Y Su, W Zheng… - Fish & Shellfish …, 2021 - Elsevier
Pseudomonas plecoglossicida is a Gram-negative aerobic rod-shaped bacterium with polar
flagella. It is the causative agent of visceral white spot disease in cultured fish, resulting in …