ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human
polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of …

Background The growing body of evidence indicating the heterogeneity of Alzheimer's
disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy …

Transcranial magnetic stimulation (TMS) is a powerful tool to probe in vivo brain circuits, as it
allows to assess several cortical properties such as excitability, plasticity and connectivity in …

APOE4 is the greatest genetic risk factor for late-onset Alzheimer's disease (AD), increasing
the risk of developing the disease by 3-fold in the 14% of the population that are carriers …

Objective Repetitive transcranial magnetic stimulation (rTMS) has been widely used in non-
invasive treatments for different neurological disorders. Few biomarkers are available for …

Objective In Alzheimer disease (AD) animal models, synaptic dysfunction has recently been
linked to a disorder of high‐frequency neuronal activity. In patients, a clear relation between …

Noninvasive brain stimulation techniques (NiBS) have gathered substantial interest in the
study of dementia, considered their possible role in help defining diagnostic biomarkers of …

Alzheimer's disease (AD) is characterized by reduced fast brain oscillations in the gamma
band (γ,> 30 Hz). Several animal studies show that inducing gamma oscillations through …

Background Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation
technique. When stimulation is applied over the primary motor cortex and coupled with …

Tauopathies are a collection of neurodegenerative diseases characterized by the
accumulation of pathogenic aggregates of the microtubule‐associated protein tau. Despite …