Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Importance Harms and benefits of opioids for chronic noncancer pain remain unclear.
Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic …

Background Diabetic peripheral neuropathic pain (DPNP) is common and often distressing.
Most guidelines recommend amitriptyline, duloxetine, pregabalin, or gabapentin as initial …

Diabetic neuropathies are the most prevalent chronic complications of diabetes. This
heterogeneous group of conditions affects different parts of the nervous system and presents …

Background Gabapentin is commonly used to treat neuropathic pain (pain due to nerve
damage). This review updates a review published in 2014, and previous reviews published …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Purpose. The pain VAS is a unidimensional measure of pain intensity (1), which has been
widely used in diverse adult populations, including those with rheumatic diseases (2–5) …

Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes, which
affects over 90% of the diabetic patients. Although pain is one of the main symptoms of …

Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …

Chronic pain is one of the most common conditions encountered by healthcare
professionals, particularly among older (≥ 65 years) patients. 1 Pain is associated with …