HIV infection can be effectively treated by lifelong administration of combination antiretroviral
therapy, but an effective vaccine will likely be required to end the HIV epidemic. Although the …

Antigen presentation by major histocompatibility complex class II (MHC-II) molecules is
crucial for eliciting an efficient immune response by CD4+ T cells and maintaining self …

Elite controllers are a heterogeneous group of people living with HIV who control viral
replication without antiretroviral therapy. There is substantial evidence that at least some …

The human immunodeficiency virus (HIV) infection of the immune cells expressing the
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …

We propose implications as to how this knowledge from natural infection can be applied in
the design and evaluation of CD8+ T-cell-based remission strategies and offer questions to …

HIV affects more than 38 million people worldwide. Although HIV can be effectively treated
by lifelong combination antiretroviral therapy, only a handful of patients have been cured …

The primary greenhouse gas is carbon dioxide (CO2), which also serves as an excellent C1
building block for the synthesis of heterocyclic compounds. The preparation and …

Understanding the complex immune mechanisms responsible for natural, drug-free HIV-1
control represents a premier avenue to find and develop interventions for a cure of HIV-1 …

T and natural killer (NK) cells are effector cells with key roles in anti-HIV immunity, including
in lymphoid tissues, the major site of HIV persistence. However, little is known about the …

As the principal effector cell population of the innate immune system, natural killer (NK) cells
may make critical contributions to natural, immune-mediated control of HIV-1 replication …