Glioblastoma: exosome and microRNA as novel diagnosis biomarkers

L Saadatpour, E Fadaee, S Fadaei… - Cancer gene …, 2016 - nature.com
Glioblastoma (GBM) is known as a tumor type, which arises from astrocytes. Several studies
indicated that GBM tumor cells are malignant. This is because of the fact that they consist of …

Biomarkers in multiple sclerosis

WJ Housley, D Pitt, DA Hafler - Clinical immunology, 2015 - Elsevier
Substantial effort has been made over the last six decades to identify biomarkers for multiple
sclerosis that can improve disease diagnosis, predict disease progression, and improve …

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

AS Doghish, O Elazazy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

MicroRNAs as biomarkers for CNS disease

P Rao, E Benito, A Fischer - Frontiers in molecular neuroscience, 2013 - frontiersin.org
For many neurological diseases, the efficacy and outcome of treatment depend on early
detection. Diagnosis is currently based on the detection of symptoms and neuroimaging …

The utility of cerebrospinal fluid analysis in patients with multiple sclerosis

M Stangel, S Fredrikson, E Meinl, A Petzold… - Nature Reviews …, 2013 - nature.com
Diagnosis of multiple sclerosis (MS) requires the exclusion of other possible diagnoses. For
this reason, the cerebrospinal fluid (CSF) should be routinely analysed in patients with a first …

Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies

KS Sheinerman, SR Umansky - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Many neurodegenerative diseases, such as Alzheimer's disease, Parkinson disease,
vascular and frontotemporal dementias, as well as other chronic neurological pathologies …

Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing

KL Burgos, A Javaherian, R Bomprezzi, L Ghaffari… - Rna, 2013 - rnajournal.cshlp.org
There has been a growing interest in using next-generation sequencing (NGS) to profile
extracellular small RNAs from the blood and cerebrospinal fluid (CSF) of patients with …

Clinical significance of miRNAs in autoimmunity

L Zhang, H Wu, M Zhao, C Chang, Q Lu - Journal of autoimmunity, 2020 - Elsevier
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …

Emerging imaging and liquid biomarkers in multiple sclerosis

AJ Gill, EM Schorr, SP Gadani… - European Journal of …, 2023 - Wiley Online Library
The advent of highly effective disease modifying therapy has transformed the landscape of
multiple sclerosis (MS) care over the last two decades. However, there remains a critical …

[HTML][HTML] Expression, regulation and function of microRNAs in multiple sclerosis

X Ma, J Zhou, Y Zhong, L Jiang, P Mu, Y Li… - … journal of medical …, 2014 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are single-stranded 19-25 nucleotide-long RNAs and have an
important role in post-transcriptional gene silencing. It has been demonstrated that miRNAs …