Microbiota medicine: towards clinical revolution
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …
Potential intestinal infection and faecal–oral transmission of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …
[HTML][HTML] Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
The tumor microenvironment (TME) influences cancer progression and therapy response.
Therefore, understanding what regulates the TME immune compartment is vital. Here we …
Therefore, understanding what regulates the TME immune compartment is vital. Here we …
Alterations of the gut microbiota in patients with coronavirus disease 2019 or H1N1 influenza
S Gu, Y Chen, Z Wu, Y Chen, H Gao… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging serious global
health problem. Gastrointestinal symptoms are common in COVID-19 patients, and severe …
health problem. Gastrointestinal symptoms are common in COVID-19 patients, and severe …
Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids
CH Kim - Cellular & molecular immunology, 2021 - nature.com
A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …
commensal bacteria play essential roles in balancing the immune system. DF, considered …
The use of RNA-based treatments in the field of cancer immunotherapy
M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …
[HTML][HTML] The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes
V Sencio, MG Machado, F Trottein - Mucosal Immunology, 2021 - Elsevier
Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut
microbiota has a critical role in pulmonary immunity and host's defense against viral …
microbiota has a critical role in pulmonary immunity and host's defense against viral …
[HTML][HTML] Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production
V Sencio, A Barthelemy, LP Tavares, MG Machado… - Cell reports, 2020 - cell.com
Secondary bacterial infections often complicate viral respiratory infections. We hypothesize
that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor …
that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor …
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …
Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration
Y Lei, L Tang, S Liu, S Hu, L Wu, Y Liu, M Yang… - Microbiome, 2021 - Springer
Background The endoglycosidase heparanase which degrades heparan sulfate
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …
proteoglycans, exerts a pro-inflammatory mediator in various inflammatory disorders …