After Edward Jenner established human vaccination over 200 years ago, attenuated
poxviruses became key players to contain the deadliest virus of its own family: Variola virus …

The field of adenovirology is undergoing rapid change in response to increasing
appreciation of the potential advantages of adenoviruses as the basis for new vaccines and …

The leading malaria vaccine in development is the circumsporozoite protein (CSP)-based
particle vaccine, RTS, S, which targets the pre-erythrocytic stage of Plasmodium falciparum …

Background The West African outbreak of Ebola virus disease that peaked in 2014 has
caused more than 11,000 deaths. The development of an effective Ebola vaccine is a priority …

Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded
recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies …

Protective immunity to the liver stage of the malaria parasite can be conferred by vaccine-
induced T cells, but no subunit vaccination approach based on cellular immunity has shown …

Human papilloma viruses can induce warts, condylomas, and other intraepithelial cervical
lesions that can progress to cancer. Cervical cancer is a serious problem in developing …

Background RH5 is a leading blood-stage candidate antigen for a Plasmodium falciparum
vaccine; however, its safety and immunogenicity in malaria-endemic populations are …

Worldwide strategies between 2010 and 2017 aimed at controlling malarial parasites
(mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence …

Introduction: Adenoviruses (Ads) have attracted researchers from across the disciplines for
several reasons. Their ability to recombine with and express the heterologous genes …